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A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome.
Bonfiglio F, Henström M, Nag A, Hadizadeh F, Zheng T, Cenit MC, Tigchelaar E, Williams F, Reznichenko A, Ek WE, Rivera NV, Homuth G, Aghdassi AA, Kacprowski T, Männikkö M, Karhunen V, Bujanda L, Rafter J, Wijmenga C, Ronkainen J, Hysi P, Zhernakova A, D'Amato M. Bonfiglio F, et al. Among authors: reznichenko a. Neurogastroenterol Motil. 2018 Sep;30(9):e13358. doi: 10.1111/nmo.13358. Epub 2018 Apr 19. Neurogastroenterol Motil. 2018. PMID: 29673008
Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts.
Ek WE, Reznichenko A, Ripke S, Niesler B, Zucchelli M, Rivera NV, Schmidt PT, Pedersen NL, Magnusson P, Talley NJ, Holliday EG, Houghton L, Gazouli M, Karamanolis G, Rappold G, Burwinkel B, Surowy H, Rafter J, Assadi G, Li L, Papadaki E, Gambaccini D, Marchi S, Colucci R, Blandizzi C, Barbaro R, Karling P, Walter S, Ohlsson B, Tornblom H, Bresso F, Andreasson A, Dlugosz A, Simren M, Agreus L, Lindberg G, Boeckxstaens G, Bellini M, Stanghellini V, Barbara G, Daly MJ, Camilleri M, Wouters MM, D'Amato M. Ek WE, et al. Among authors: reznichenko a. Gut. 2015 Nov;64(11):1774-82. doi: 10.1136/gutjnl-2014-307997. Epub 2014 Sep 23. Gut. 2015. PMID: 25248455
Targeted Analysis of Serum Proteins Encoded at Known Inflammatory Bowel Disease Risk Loci.
Drobin K, Assadi G, Hong MG, Andersson E, Fredolini C, Forsström B, Reznichenko A, Akhter T, Ek WE, Bonfiglio F, Hansen MB, Sandberg K, Greco D, Repsilber D, Schwenk JM, D'Amato M, Halfvarson J. Drobin K, et al. Among authors: reznichenko a. Inflamm Bowel Dis. 2019 Jan 10;25(2):306-316. doi: 10.1093/ibd/izy326. Inflamm Bowel Dis. 2019. PMID: 30358838 Free PMC article.
Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Wang Q, Dhindsa RS, Carss K, Harper AR, Nag A, Tachmazidou I, Vitsios D, Deevi SVV, Mackay A, Muthas D, Hühn M, Monkley S, Olsson H; AstraZeneca Genomics Initiative; Wasilewski S, Smith KR, March R, Platt A, Haefliger C, Petrovski S. Wang Q, et al. Nature. 2021 Sep;597(7877):527-532. doi: 10.1038/s41586-021-03855-y. Epub 2021 Aug 10. Nature. 2021. PMID: 34375979 Free PMC article.
Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci.
Thio CHL, Reznichenko A, van der Most PJ, Kamali Z, Vaez A, Smit JH, Penninx BWJH, Haller T, Mihailov E, Metspalu A, Damman J, de Borst MH, van der Harst P, Verweij N, Navis GJ, Gansevoort RT, Nolte IM, Snieder H; Lifelines Cohort Study group. Thio CHL, et al. Among authors: reznichenko a. Am J Nephrol. 2019;49(3):193-202. doi: 10.1159/000496930. Epub 2019 Feb 26. Am J Nephrol. 2019. PMID: 30808845 Free article.
Deficiency of T-type voltage-gated calcium channels results in attenuated weight gain and improved endothelium-dependent dilatation of resistance vessels induced by a high-fat diet in mice.
Rosenstand K, Andersen K, Terp R, Gennemark P, Ellman DG, Reznichenko A, Lambertsen KL, Vanhoutte PM, Hansen PBL, Svenningsen P. Rosenstand K, et al. Among authors: reznichenko a. J Physiol Biochem. 2020 Feb;76(1):135-145. doi: 10.1007/s13105-020-00728-2. Epub 2020 Feb 3. J Physiol Biochem. 2020. PMID: 32016773
CUBN as a novel locus for end-stage renal disease: insights from renal transplantation.
Reznichenko A, Snieder H, van den Born J, de Borst MH, Damman J, van Dijk MC, van Goor H, Hepkema BG, Hillebrands JL, Leuvenink HG, Niesing J, Bakker SJ, Seelen M, Navis G; REGaTTA (REnal GeneTics TrAnsplantation) Groningen group. Reznichenko A, et al. PLoS One. 2012;7(5):e36512. doi: 10.1371/journal.pone.0036512. Epub 2012 May 4. PLoS One. 2012. PMID: 22574174 Free PMC article.
Lectin complement pathway gene profile of the donor and recipient does not influence graft outcome after kidney transplantation.
Damman J, Kok JL, Snieder H, Leuvenink HG, van Goor H, Hillebrands JL, van Dijk MC, Hepkema BG, Reznichenko A, van den Born J, de Borst MH, Bakker SJ, Navis GJ, Ploeg RJ, Seelen MA. Damman J, et al. Among authors: reznichenko a. Mol Immunol. 2012 Feb;50(1-2):1-8. doi: 10.1016/j.molimm.2011.11.009. Epub 2011 Dec 15. Mol Immunol. 2012. PMID: 22173059
63 results