Ripka WC - Search Results

1

Study of the shape of the binding site of bovine opsin using 10-substituted retinal isomers.

Asato AE, Denny M, Matsumoto H, Mirzadegan T, Ripka WC, Crescitelli F, Liu RS. Asato AE, et al. Among authors: ripka wc. Biochemistry. 1986 Nov 4;25(22):7021-6. doi: 10.1021/bi00370a039. Biochemistry. 1986. PMID: 2948554

2

Modeling rhodopsin, a member of G-protein coupled receptors, by computer graphics. Interpretation of chemical shifts of fluorinated rhodopsins.

Mirzadegan T, Humblet C, Ripka WC, Colmenares LU, Liu RS. Mirzadegan T, et al. Among authors: ripka wc. Photochem Photobiol. 1992 Dec;56(6):883-93. doi: 10.1111/j.1751-1097.1992.tb09709.x. Photochem Photobiol. 1992. PMID: 1492134

3

Molecular modeling in the design of phospholipase A2 inhibitors.

Ripka WC, Sipio WJ, Galbraith WG. Ripka WC, et al. J Cell Biochem. 1989 Jul;40(3):279-86. doi: 10.1002/jcb.240400304. J Cell Biochem. 1989. PMID: 2777907

4

Synthesis and NMR conformational analysis of a beta-turn mimic incorporated into gramicidin S. A general approach to evaluate beta-turn peptidomimetics.

Bach AC 2nd, Markwalder JA, Ripka WC. Bach AC 2nd, et al. Among authors: ripka wc. Int J Pept Protein Res. 1991 Oct;38(4):314-23. doi: 10.1111/j.1399-3011.1991.tb01510.x. Int J Pept Protein Res. 1991. PMID: 1724663

5

Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic.

Krishnan R, Tulinsky A, Vlasuk GP, Pearson D, Vallar P, Bergum P, Brunck TK, Ripka WC. Krishnan R, et al. Among authors: ripka wc. Protein Sci. 1996 Mar;5(3):422-33. doi: 10.1002/pro.5560050303. Protein Sci. 1996. PMID: 8868478 Free PMC article.

6

Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1.

Levy OE, Semple JE, Lim ML, Reiner J, Rote WE, Dempsey E, Richard BM, Zhang E, Tulinsky A, Ripka WC, Nutt RF. Levy OE, et al. Among authors: ripka wc. J Med Chem. 1996 Nov 8;39(23):4527-30. doi: 10.1021/jm960607j. J Med Chem. 1996. PMID: 8917638 No abstract available.

7

Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties.

Semple JE, Rowley DC, Brunck TK, Ha-Uong T, Minami NK, Owens TD, Tamura SY, Goldman EA, Siev DV, Ardecky RJ, Carpenter SH, Ge Y, Richard BM, Nolan TG, Håkanson K, Tulinsky A, Nutt RF, Ripka WC. Semple JE, et al. Among authors: ripka wc. J Med Chem. 1996 Nov 8;39(23):4531-6. doi: 10.1021/jm960572n. J Med Chem. 1996. PMID: 8917639 No abstract available.

8

Inhibition of fructose-1,6-bisphosphatase by a new class of allosteric effectors.

Choe JY, Nelson SW, Arienti KL, Axe FU, Collins TL, Jones TK, Kimmich RD, Newman MJ, Norvell K, Ripka WC, Romano SJ, Short KM, Slee DH, Fromm HJ, Honzatko RB. Choe JY, et al. Among authors: ripka wc. J Biol Chem. 2003 Dec 19;278(51):51176-83. doi: 10.1074/jbc.M308396200. Epub 2003 Oct 6. J Biol Chem. 2003. PMID: 14530289 Free article.

9

New thrombin inhibitors in cardiovascular disease.

Ripka WC. Ripka WC. Curr Opin Chem Biol. 1997 Aug;1(2):242-53. doi: 10.1016/s1367-5931(97)80016-6. Curr Opin Chem Biol. 1997. PMID: 9667850 Review.

10

Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.

Andersen HS, Olsen OH, Iversen LF, Sørensen AL, Mortensen SB, Christensen MS, Branner S, Hansen TK, Lau JF, Jeppesen L, Moran EJ, Su J, Bakir F, Judge L, Shahbaz M, Collins T, Vo T, Newman MJ, Ripka WC, Møller NP. Andersen HS, et al. Among authors: ripka wc. J Med Chem. 2002 Sep 26;45(20):4443-59. doi: 10.1021/jm0209026. J Med Chem. 2002. PMID: 12238924

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