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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S,… See abstract for full author list ➔ Davies G, et al. Among authors: ritchie sj. Nat Commun. 2018 May 29;9(1):2098. doi: 10.1038/s41467-018-04362-x. Nat Commun. 2018. PMID: 29844566 Free PMC article.
The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936.
Marioni RE, Shah S, McRae AF, Ritchie SJ, Muniz-Terrera G, Harris SE, Gibson J, Redmond P, Cox SR, Pattie A, Corley J, Taylor A, Murphy L, Starr JM, Horvath S, Visscher PM, Wray NR, Deary IJ. Marioni RE, et al. Among authors: ritchie sj. Int J Epidemiol. 2015 Aug;44(4):1388-96. doi: 10.1093/ije/dyu277. Epub 2015 Jan 22. Int J Epidemiol. 2015. PMID: 25617346 Free PMC article.
Association of allostatic load with brain structure and cognitive ability in later life.
Booth T, Royle NA, Corley J, Gow AJ, Valdés Hernández Mdel C, Muñoz Maniega S, Ritchie SJ, Bastin ME, Starr JM, Wardlaw JM, Deary IJ. Booth T, et al. Among authors: ritchie sj. Neurobiol Aging. 2015 Mar;36(3):1390-9. doi: 10.1016/j.neurobiolaging.2014.12.020. Epub 2014 Dec 22. Neurobiol Aging. 2015. PMID: 25659881 Free PMC article.
Coupled changes in brain white matter microstructure and fluid intelligence in later life.
Ritchie SJ, Bastin ME, Tucker-Drob EM, Maniega SM, Engelhardt LE, Cox SR, Royle NA, Gow AJ, Corley J, Pattie A, Taylor AM, Valdés Hernández Mdel C, Starr JM, Wardlaw JM, Deary IJ. Ritchie SJ, et al. J Neurosci. 2015 Jun 3;35(22):8672-82. doi: 10.1523/JNEUROSCI.0862-15.2015. J Neurosci. 2015. PMID: 26041932 Free PMC article.
Beyond a bigger brain: Multivariable structural brain imaging and intelligence.
Ritchie SJ, Booth T, Valdés Hernández MD, Corley J, Maniega SM, Gow AJ, Royle NA, Pattie A, Karama S, Starr JM, Bastin ME, Wardlaw JM, Deary IJ. Ritchie SJ, et al. Intelligence. 2015 Jul-Aug;51:47-56. doi: 10.1016/j.intell.2015.05.001. Intelligence. 2015. PMID: 26240470 Free PMC article.
102 results