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The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, White AR, Crouch PJ, Lim S, Leong SL, Wilkins S, George J, Roberts BR, Pham CL, Liu X, Chiu FC, Shackleford DM, Powell AK, Masters CL, Bush AI, O'Keefe G, Culvenor JG, Cappai R, Cherny RA, Donnelly PS, Hill AF, Finkelstein DI, Barnham KJ. Hung LW, et al. Among authors: roberts br. J Exp Med. 2012 Apr 9;209(4):837-54. doi: 10.1084/jem.20112285. Epub 2012 Apr 2. J Exp Med. 2012. PMID: 22473957 Free PMC article.
Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease.
Rembach A, Doecke JD, Roberts BR, Watt AD, Faux NG, Volitakis I, Pertile KK, Rumble RL, Trounson BO, Fowler CJ, Wilson W, Ellis KA, Martins RN, Rowe CC, Villemagne VL, Ames D, Masters CL, AIBL research group, Bush AI. Rembach A, et al. Among authors: roberts br. J Alzheimers Dis. 2013;34(1):171-82. doi: 10.3233/JAD-121474. J Alzheimers Dis. 2013. PMID: 23168449
Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease.
Rembach A, Faux NG, Watt AD, Pertile KK, Rumble RL, Trounson BO, Fowler CJ, Roberts BR, Perez KA, Li QX, Laws SM, Taddei K, Rainey-Smith S, Robertson JS, Vandijck M, Vanderstichele H, Barnham KJ, Ellis KA, Szoeke C, Macaulay L, Rowe CC, Villemagne VL, Ames D, Martins RN, Bush AI, Masters CL; AIBL research group. Rembach A, et al. Among authors: roberts br. Alzheimers Dement. 2014 Jan;10(1):53-61. doi: 10.1016/j.jalz.2012.12.006. Epub 2013 Mar 13. Alzheimers Dement. 2014. PMID: 23491263
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry.
Hare DJ, Grubman A, Ryan TM, Lothian A, Liddell JR, Grimm R, Matsuda T, Doble PA, Cherny RA, Bush AI, White AR, Masters CL, Roberts BR. Hare DJ, et al. Among authors: roberts br. Metallomics. 2013 Dec;5(12):1656-62. doi: 10.1039/c3mt00227f. Epub 2013 Oct 17. Metallomics. 2013. PMID: 24132241
Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.
Roberts BR, Lim NK, McAllum EJ, Donnelly PS, Hare DJ, Doble PA, Turner BJ, Price KA, Lim SC, Paterson BM, Hickey JL, Rhoads TW, Williams JR, Kanninen KM, Hung LW, Liddell JR, Grubman A, Monty JF, Llanos RM, Kramer DR, Mercer JF, Bush AI, Masters CL, Duce JA, Li QX, Beckman JS, Barnham KJ, White AR, Crouch PJ. Roberts BR, et al. J Neurosci. 2014 Jun 4;34(23):8021-31. doi: 10.1523/JNEUROSCI.4196-13.2014. J Neurosci. 2014. PMID: 24899723 Free PMC article.
Decreased plasma iron in Alzheimer's disease is due to transferrin desaturation.
Hare DJ, Doecke JD, Faux NG, Rembach A, Volitakis I, Fowler CJ, Grimm R, Doble PA, Cherny RA, Masters CL, Bush AI, Roberts BR. Hare DJ, et al. Among authors: roberts br. ACS Chem Neurosci. 2015 Mar 18;6(3):398-402. doi: 10.1021/cn5003557. Epub 2015 Jan 23. ACS Chem Neurosci. 2015. PMID: 25588002
194 results