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Page 1
Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action.
Cairns J, Ingle JN, Dudenkov TM, Kalari KR, Carlson EE, Na J, Buzdar AU, Robson ME, Ellis MJ, Goss PE, Shepherd LE, Goodnature B, Goetz MP, Weinshilboum RM, Li H, Bari MG, Wang L. Cairns J, et al. Among authors: robson me. JCI Insight. 2020 Aug 20;5(16):e137571. doi: 10.1172/jci.insight.137571. JCI Insight. 2020. PMID: 32701512 Free PMC article. Clinical Trial.
Update on hereditary breast cancer.
Smith KL, Robson ME. Smith KL, et al. Among authors: robson me. Curr Oncol Rep. 2006 Jan;8(1):14-21. doi: 10.1007/s11912-006-0004-x. Curr Oncol Rep. 2006. PMID: 16464398 Review.
Variation in anastrozole metabolism and pharmacodynamics in women with early breast cancer.
Ingle JN, Buzdar AU, Schaid DJ, Goetz MP, Batzler A, Robson ME, Northfelt DW, Olson JE, Perez EA, Desta Z, Weintraub RA, Williard CV, Flockhart DA, Weinshilboum RM. Ingle JN, et al. Among authors: robson me. Cancer Res. 2010 Apr 15;70(8):3278-86. doi: 10.1158/0008-5472.CAN-09-3024. Epub 2010 Mar 30. Cancer Res. 2010. PMID: 20354183 Free PMC article.
TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, Schaid DJ, Nakamura Y, Weinshilboum RM. Liu M, et al. Among authors: robson me. Mol Endocrinol. 2013 Apr;27(4):657-70. doi: 10.1210/me.2012-1397. Epub 2013 Mar 21. Mol Endocrinol. 2013. PMID: 23518928 Free PMC article. Clinical Trial.
Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole.
Ingle JN, Kalari KR, Buzdar AU, Robson ME, Goetz MP, Desta Z, Barman P, Dudenkov TT, Northfelt DW, Perez EA, Flockhart DA, Williard CV, Wang L, Weinshilboum RM. Ingle JN, et al. Among authors: robson me. Steroids. 2015 Jul;99(Pt A):32-8. doi: 10.1016/j.steroids.2014.08.007. Epub 2014 Aug 24. Steroids. 2015. PMID: 25163006 Free PMC article. Clinical Trial.
SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
Dudenkov TM, Ingle JN, Buzdar AU, Robson ME, Kubo M, Ibrahim-Zada I, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Barman P, Goetz MP, Northfelt DW, Moreno-Aspita A, Williard CV, Kalari KR, Nakamura Y, Wang L, Weinshilboum RM. Dudenkov TM, et al. Among authors: robson me. Breast Cancer Res Treat. 2017 Jul;164(1):189-199. doi: 10.1007/s10549-017-4243-3. Epub 2017 Apr 20. Breast Cancer Res Treat. 2017. PMID: 28429243 Free PMC article.
Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2.
Dudenkov TM, Liu D, Cairns J, Devarajan S, Zhuang Y, Ingle JN, Buzdar AU, Robson ME, Kubo M, Batzler A, Barman P, Jenkins GD, Carlson EE, Goetz MP, Northfelt DW, Moreno-Aspitia A, Desta Z, Reid JM, Kalari KR, Wang L, Weinshilboum RM. Dudenkov TM, et al. Among authors: robson me. Clin Pharmacol Ther. 2019 Jul;106(1):219-227. doi: 10.1002/cpt.1359. Epub 2019 Mar 18. Clin Pharmacol Ther. 2019. PMID: 30648747 Free PMC article.
Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer.
Ingle JN, Kalari KR, Barman P, Shepherd LE, Ellis MJ, Goss PE, Buzdar AU, Robson ME, Cairns J, Carlson EE, Eyman Casey A, Hoskin TL, Goodnature BA, Haddad TC, Goetz MP, Weinshilboum RM, Wang L. Ingle JN, et al. Among authors: robson me. Pharmacogenet Genomics. 2021 Jan;31(1):1-9. doi: 10.1097/FPC.0000000000000415. Pharmacogenet Genomics. 2021. PMID: 32649577 Free PMC article.
Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors.
Razavi P, Dickler MN, Shah PD, Toy W, Brown DN, Won HH, Li BT, Shen R, Vasan N, Modi S, Jhaveri K, Caravella BA, Patil S, Selenica P, Zamora S, Cowan AM, Comen E, Singh A, Covey A, Berger MF, Hudis CA, Norton L, Nagy RJ, Odegaard JI, Lanman RB, Solit DB, Robson ME, Lacouture ME, Brogi E, Reis-Filho JS, Moynahan ME, Scaltriti M, Chandarlapaty S. Razavi P, et al. Among authors: robson me. Nat Cancer. 2020 Apr;1(4):382-393. doi: 10.1038/s43018-020-0047-1. Epub 2020 Mar 23. Nat Cancer. 2020. PMID: 32864625 Free PMC article.
Treatment of hereditary breast cancer.
Robson ME. Robson ME. Semin Oncol. 2007 Oct;34(5):384-91. doi: 10.1053/j.seminoncol.2007.07.011. Semin Oncol. 2007. PMID: 17920892 Review.
227 results