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A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, Hottenga JJ, Trompet S, Müller-Nurasyid M, Zhao JH, Brody JA, Kleber ME, Guo X, Wang JJ, Auer PL, Attia JR, Yanek LR, Ahluwalia TS, Lahti J, Venturini C, Tanaka T, Bielak LF, Joshi PK, Rocanin-Arjo A, Kolcic I, Navarro P, Rose LM, Oldmeadow C, Riess H, Mazur J, Basu S, Goel A, Yang Q, Ghanbari M, Willemsen G, Rumley A, Fiorillo E, de Craen AJ, Grotevendt A, Scott R, Taylor KD, Delgado GE, Yao J, Kifley A, Kooperberg C, Qayyum R, Lopez LM, Berentzen TL, Räikkönen K, Mangino M, Bandinelli S, Peyser PA, Wild S, Trégouët DA, Wright AF, Marten J, Zemunik T, Morrison AC, Sennblad B, Tofler G, de Maat MP, de Geus EJ, Lowe GD, Zoledziewska M, Sattar N, Binder H, Völker U, Waldenberger M, Khaw KT, Mcknight B, Huang J, Jenny NS, Holliday EG, Qi L, Mcevoy MG, Becker DM, Starr JM, Sarin AP, Hysi PG, Hernandez DG, Jhun MA, Campbell H, Hamsten A, Rivadeneira F, Mcardle WL, Slagboom PE, Zeller T, Koenig W, Psaty BM, Haritunians T, Liu J, Palotie A, Uitterlinden AG, Stott DJ, Hofman A, Franco OH, Polasek O, Rudan I, Morange PE, Wilson JF, Kardia SL, Ferrucci L, Spector TD, Eri… See abstract for full author list ➔ de Vries PS, et al. Among authors: rocanin arjo a. Hum Mol Genet. 2016 Jan 15;25(2):358-70. doi: 10.1093/hmg/ddv454. Epub 2015 Nov 10. Hum Mol Genet. 2016. PMID: 26561523 Free PMC article.
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.
Germain M, Chasman DI, de Haan H, Tang W, Lindström S, Weng LC, de Andrade M, de Visser MC, Wiggins KL, Suchon P, Saut N, Smadja DM, Le Gal G, van Hylckama Vlieg A, Di Narzo A, Hao K, Nelson CP, Rocanin-Arjo A, Folkersen L, Monajemi R, Rose LM, Brody JA, Slagboom E, Aïssi D, Gagnon F, Deleuze JF, Deloukas P, Tzourio C, Dartigues JF, Berr C, Taylor KD, Civelek M, Eriksson P; Cardiogenics Consortium; Psaty BM, Houwing-Duitermaat J, Goodall AH, Cambien F, Kraft P, Amouyel P, Samani NJ, Basu S, Ridker PM, Rosendaal FR, Kabrhel C, Folsom AR, Heit J, Reitsma PH, Trégouët DA, Smith NL, Morange PE. Germain M, et al. Among authors: rocanin arjo a. Am J Hum Genet. 2015 Apr 2;96(4):532-42. doi: 10.1016/j.ajhg.2015.01.019. Epub 2015 Mar 12. Am J Hum Genet. 2015. PMID: 25772935 Free PMC article.
A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential.
Rocanin-Arjo A, Cohen W, Carcaillon L, Frère C, Saut N, Letenneur L, Alhenc-Gelas M, Dupuy AM, Bertrand M, Alessi MC, Germain M, Wild PS, Zeller T, Cambien F, Goodall AH, Amouyel P, Scarabin PY, Trégouët DA, Morange PE; CardioGenics Consortium. Rocanin-Arjo A, et al. Blood. 2014 Jan 30;123(5):777-85. doi: 10.1182/blood-2013-10-529628. Epub 2013 Dec 19. Blood. 2014. PMID: 24357727 Free article.
Genome-wide investigation of DNA methylation marks associated with FV Leiden mutation.
Aïssi D, Dennis J, Ladouceur M, Truong V, Zwingerman N, Rocanin-Arjo A, Germain M, Paton TA, Morange PE, Gagnon F, Trégouët DA. Aïssi D, et al. Among authors: rocanin arjo a. PLoS One. 2014 Sep 29;9(9):e108087. doi: 10.1371/journal.pone.0108087. eCollection 2014. PLoS One. 2014. PMID: 25265411 Free PMC article.
Thrombin generation potential and whole-blood DNA methylation.
Rocañín-Arjó A, Dennis J, Suchon P, Aïssi D, Truong V, Trégouët DA, Gagnon F, Morange PE. Rocañín-Arjó A, et al. Thromb Res. 2015 Mar;135(3):561-4. doi: 10.1016/j.thromres.2014.12.010. Epub 2014 Dec 12. Thromb Res. 2015. PMID: 25563678 No abstract available.
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements.
Burbage M, Rocañín-Arjó A, Baudon B, Arribas YA, Merlotti A, Rookhuizen DC, Heurtebise-Chrétien S, Ye M, Houy A, Burgdorf N, Suarez G, Gros M, Sadacca B, Carrascal M, Garmilla A, Bohec M, Baulande S, Lombard B, Loew D, Waterfall JJ, Stern MH, Goudot C, Amigorena S. Burbage M, et al. Among authors: rocanin arjo a. Sci Immunol. 2023 Feb 3;8(80):eabm6360. doi: 10.1126/sciimmunol.abm6360. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735776
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer.
Merlotti A, Sadacca B, Arribas YA, Ngoma M, Burbage M, Goudot C, Houy A, Rocañín-Arjó A, Lalanne A, Seguin-Givelet A, Lefevre M, Heurtebise-Chrétien S, Baudon B, Oliveira G, Loew D, Carrascal M, Wu CJ, Lantz O, Stern MH, Girard N, Waterfall JJ, Amigorena S. Merlotti A, et al. Among authors: rocanin arjo a. Sci Immunol. 2023 Feb 3;8(80):eabm6359. doi: 10.1126/sciimmunol.abm6359. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735774
Systems biology analysis reveals role of MDM2 in diabetic nephropathy.
Saito R, Rocanin-Arjo A, You YH, Darshi M, Van Espen B, Miyamoto S, Pham J, Pu M, Romoli S, Natarajan L, Ju W, Kretzler M, Nelson R, Ono K, Thomasova D, Mulay SR, Ideker T, D'Agati V, Beyret E, Belmonte JCI, Anders HJ, Sharma K. Saito R, et al. Among authors: rocanin arjo a. JCI Insight. 2016 Oct 20;1(17):e87877. doi: 10.1172/jci.insight.87877. JCI Insight. 2016. PMID: 27777973 Free PMC article.