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IL-36γ is secreted through an unconventional pathway using the Gasdermin D and P2X7R membrane pores.
Manzanares-Meza LD, Gutiérrez-Román CI, Jiménez-Pineda A, Castro-Martínez F, Patiño-López G, Rodríguez-Arellano E, Valle-Rios R, Ortíz-Navarrete VF, Medina-Contreras O. Manzanares-Meza LD, et al. Among authors: rodriguez arellano e. Front Immunol. 2022 Aug 18;13:979749. doi: 10.3389/fimmu.2022.979749. eCollection 2022. Front Immunol. 2022. PMID: 36059446 Free PMC article.
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
SIGMA Type 2 Diabetes Consortium; Williams AL, Jacobs SB, Moreno-Macías H, Huerta-Chagoya A, Churchhouse C, Márquez-Luna C, García-Ortíz H, Gómez-Vázquez MJ, Burtt NP, Aguilar-Salinas CA, González-Villalpando C, Florez JC, Orozco L, Haiman CA, Tusié-Luna T, Altshuler D. SIGMA Type 2 Diabetes Consortium, et al. Nature. 2014 Feb 6;506(7486):97-101. doi: 10.1038/nature12828. Epub 2013 Dec 25. Nature. 2014. PMID: 24390345 Free PMC article.
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes.
Majithia AR, Flannick J, Shahinian P, Guo M, Bray MA, Fontanillas P, Gabriel SB; GoT2D Consortium; NHGRI JHS/FHS Allelic Spectrum Project; SIGMA T2D Consortium; T2D-GENES Consortium; Rosen ED, Altshuler D. Majithia AR, et al. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13127-32. doi: 10.1073/pnas.1410428111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157153 Free PMC article.
[Diagnostic criteria for hypoalphalipoproteinemia and the threshold associated with cardiovascular protection in a Mexican Mestizo population].
López-Hernández D, Meaney-Martínez A, Sánchez-Hernández OE, Rodríguez-Arellano E, Beltrán-Lagunes L, Estrada-García T. López-Hernández D, et al. Among authors: rodriguez arellano e. Med Clin (Barc). 2012 May 12;138(13):551-6. doi: 10.1016/j.medcli.2011.09.037. Epub 2012 Mar 6. Med Clin (Barc). 2012. PMID: 22401724 Spanish.