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sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
Suárez-Calvet M, Kleinberger G, Araque Caballero MÁ, Brendel M, Rominger A, Alcolea D, Fortea J, Lleó A, Blesa R, Gispert JD, Sánchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, Traschütz A, Heneka MT, Struyfs H, Engelborghs S, Sleegers K, Van Broeckhoven C, Zetterberg H, Nellgård B, Blennow K, Crispin A, Ewers M, Haass C. Suárez-Calvet M, et al. Among authors: rominger a. EMBO Mol Med. 2016 May 2;8(5):466-76. doi: 10.15252/emmm.201506123. Print 2016 May. EMBO Mol Med. 2016. PMID: 26941262 Free PMC article.
Quantitative longitudinal interrelationships between brain metabolism and amyloid deposition during a 2-year follow-up in patients with early Alzheimer's disease.
Förster S, Yousefi BH, Wester HJ, Klupp E, Rominger A, Förstl H, Kurz A, Grimmer T, Drzezga A. Förster S, et al. Among authors: rominger a. Eur J Nucl Med Mol Imaging. 2012 Dec;39(12):1927-36. doi: 10.1007/s00259-012-2230-9. Epub 2012 Aug 28. Eur J Nucl Med Mol Imaging. 2012. PMID: 22926714
Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET.
Rominger A, Brendel M, Burgold S, Keppler K, Baumann K, Xiong G, Mille E, Gildehaus FJ, Carlsen J, Schlichtiger J, Niedermoser S, Wängler B, Cumming P, Steiner H, Herms J, Haass C, Bartenstein P. Rominger A, et al. J Nucl Med. 2013 Jul;54(7):1127-34. doi: 10.2967/jnumed.112.114660. Epub 2013 May 31. J Nucl Med. 2013. PMID: 23729696 Free article.
Depressive symptoms accelerate cognitive decline in amyloid-positive MCI patients.
Brendel M, Pogarell O, Xiong G, Delker A, Bartenstein P, Rominger A; Alzheimer’s Disease Neuroimaging Initiative. Brendel M, et al. Among authors: rominger a. Eur J Nucl Med Mol Imaging. 2015 Apr;42(5):716-24. doi: 10.1007/s00259-014-2975-4. Epub 2015 Jan 29. Eur J Nucl Med Mol Imaging. 2015. PMID: 25631614 Free PMC article.
Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment.
Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Brendel M, et al. Among authors: rominger a. Mol Psychiatry. 2015 Oct;20(10):1179-87. doi: 10.1038/mp.2015.74. Epub 2015 Jun 9. Mol Psychiatry. 2015. PMID: 26055427 Free PMC article.
Monitoring of chronic γ-secretase modulator treatment by serial amyloid-PET.
Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Brendel M, et al. Among authors: rominger a. Mol Psychiatry. 2015 Oct;20(10):1141. doi: 10.1038/mp.2015.146. Mol Psychiatry. 2015. PMID: 26401838 No abstract available.
318 results