Roodveldt C - Search Results

1

Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia.

Leal-Lasarte MM, Franco JM, Labrador-Garrido A, Pozo D, Roodveldt C. Leal-Lasarte MM, et al. Among authors: roodveldt c. FASEB J. 2017 Jul;31(7):2797-2816. doi: 10.1096/fj.201601163R. Epub 2017 Mar 23. FASEB J. 2017. PMID: 28336525

2

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip.

Roodveldt C, Bertoncini CW, Andersson A, van der Goot AT, Hsu ST, Fernández-Montesinos R, de Jong J, van Ham TJ, Nollen EA, Pozo D, Christodoulou J, Dobson CM. Roodveldt C, et al. EMBO J. 2009 Dec 2;28(23):3758-70. doi: 10.1038/emboj.2009.298. Epub 2009 Oct 29. EMBO J. 2009. PMID: 19875982 Free PMC article.

3

Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.

Roodveldt C, Labrador-Garrido A, Gonzalez-Rey E, Fernandez-Montesinos R, Caro M, Lachaud CC, Waudby CA, Delgado M, Dobson CM, Pozo D. Roodveldt C, et al. PLoS One. 2010 Oct 26;5(10):e13481. doi: 10.1371/journal.pone.0013481. PLoS One. 2010. PMID: 21048992 Free PMC article.

4

A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein.

Roodveldt C, Andersson A, De Genst EJ, Labrador-Garrido A, Buell AK, Dobson CM, Tartaglia GG, Vendruscolo M. Roodveldt C, et al. Biochemistry. 2012 Nov 6;51(44):8771-8. doi: 10.1021/bi300558q. Epub 2012 Oct 22. Biochemistry. 2012. PMID: 23003198

5

Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.

Roodveldt C, Labrador-Garrido A, Gonzalez-Rey E, Lachaud CC, Guilliams T, Fernandez-Montesinos R, Benitez-Rondan A, Robledo G, Hmadcha A, Delgado M, Dobson CM, Pozo D. Roodveldt C, et al. PLoS One. 2013 Nov 13;8(11):e79160. doi: 10.1371/journal.pone.0079160. eCollection 2013. PLoS One. 2013. PMID: 24236103 Free PMC article.

6

Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype.

Labrador-Garrido A, Cejudo-Guillén M, Klippstein R, De Genst EJ, Tomas-Gallardo L, Leal MM, Villadiego J, Toledo-Aral JJ, Dobson CM, Pozo D, Roodveldt C. Labrador-Garrido A, et al. Among authors: roodveldt c. Immun Inflamm Dis. 2014 Dec;2(4):226-38. doi: 10.1002/iid3.39. Epub 2014 Dec 5. Immun Inflamm Dis. 2014. PMID: 25866630 Free PMC article.

7

Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α-synuclein-elicited immune response.

Labrador-Garrido A, Cejudo-Guillén M, Daturpalli S, Leal MM, Klippstein R, De Genst EJ, Villadiego J, Toledo-Aral JJ, Dobson CM, Jackson SE, Pozo D, Roodveldt C. Labrador-Garrido A, et al. Among authors: roodveldt c. FASEB J. 2016 Feb;30(2):564-77. doi: 10.1096/fj.15-275131. Epub 2015 Oct 6. FASEB J. 2016. PMID: 26443817

8

The 'Omics' of Amyotrophic Lateral Sclerosis.

Caballero-Hernandez D, Toscano MG, Cejudo-Guillen M, Garcia-Martin ML, Lopez S, Franco JM, Quintana FJ, Roodveldt C, Pozo D. Caballero-Hernandez D, et al. Among authors: roodveldt c. Trends Mol Med. 2016 Jan;22(1):53-67. doi: 10.1016/j.molmed.2015.11.001. Epub 2015 Dec 13. Trends Mol Med. 2016. PMID: 26691296 Review.

9

Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.

Villadiego J, Labrador-Garrido A, Franco JM, Leal-Lasarte M, De Genst EJ, Dobson CM, Pozo D, Toledo-Aral JJ, Roodveldt C. Villadiego J, et al. Among authors: roodveldt c. Glia. 2018 Jan;66(1):191-205. doi: 10.1002/glia.23237. Epub 2017 Oct 11. Glia. 2018. PMID: 29024008

10

Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers.

Mannini B, Vecchi G, Labrador-Garrido A, Fabre B, Fani G, Franco JM, Lilley K, Pozo D, Vendruscolo M, Chiti F, Dobson CM, Roodveldt C. Mannini B, et al. Among authors: roodveldt c. ACS Chem Neurosci. 2019 Aug 21;10(8):3464-3478. doi: 10.1021/acschemneuro.9b00088. Epub 2019 Aug 2. ACS Chem Neurosci. 2019. PMID: 31313906

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