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Genome-Wide Association Study and Identification of a Protective Missense Variant on Lipoprotein(a) Concentration: Protective Missense Variant on Lipoprotein(a) Concentration-Brief Report.
Said MA, Yeung MW, van de Vegte YJ, Benjamins JW, Dullaart RPF, Ruotsalainen S, Ripatti S, Natarajan P, Juarez-Orozco LE, Verweij N, van der Harst P. Said MA, et al. Among authors: ruotsalainen s. Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):1792-1800. doi: 10.1161/ATVBAHA.120.315300. Epub 2021 Mar 18. Arterioscler Thromb Vasc Biol. 2021. PMID: 33730874 Free article.
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P; NHLBI TOPMed Lipids Working Group. Zekavat SM, et al. Among authors: ruotsalainen s. Nat Commun. 2018 Jul 4;9(1):2606. doi: 10.1038/s41467-018-04668-w. Nat Commun. 2018. PMID: 29973585 Free PMC article.
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P; NHLBI TOPMed Lipids Working Group. Zekavat SM, et al. Among authors: ruotsalainen s. Nat Commun. 2018 Aug 23;9(1):3493. doi: 10.1038/s41467-018-05975-y. Nat Commun. 2018. PMID: 30140049 Free PMC article.
Genomic prediction of alcohol-related morbidity and mortality.
Kiiskinen T, Mars NJ, Palviainen T, Koskela J, Rämö JT, Ripatti P, Ruotsalainen S; FinnGen, GSCAN Consortium; Palotie A, Madden PAF, Rose RJ, Kaprio J, Salomaa V, Mäkelä P, Havulinna AS, Ripatti S. Kiiskinen T, et al. Among authors: ruotsalainen s. Transl Psychiatry. 2020 Jan 21;10(1):23. doi: 10.1038/s41398-019-0676-2. Transl Psychiatry. 2020. PMID: 32066667 Free PMC article.
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P; NHLBI TOPMed Lipids Working Group. Zekavat SM, et al. Among authors: ruotsalainen s. Nat Commun. 2020 Apr 1;11(1):1715. doi: 10.1038/s41467-020-15236-6. Nat Commun. 2020. PMID: 32238811 Free PMC article.
Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.
Strausz S, Ruotsalainen S, Ollila HM, Karjalainen J, Kiiskinen T, Reeve M, Kurki M, Mars N, Havulinna AS, Luonsi E, Mansour Aly D, Ahlqvist E, Teder-Laving M, Palta P, Groop L, Mägi R, Mäkitie A, Salomaa V, Bachour A, Tuomi T; FinnGen; Palotie A, Palotie T, Ripatti S. Strausz S, et al. Among authors: ruotsalainen s. Eur Respir J. 2021 May 6;57(5):2003091. doi: 10.1183/13993003.03091-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33243845 Free article.
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
Saarentaus EC, Havulinna AS, Mars N, Ahola-Olli A, Kiiskinen TTJ, Partanen J, Ruotsalainen S, Kurki M, Urpa LM, Chen L, Perola M, Salomaa V, Veijola J, Männikkö M, Hall IM, Pietiläinen O, Kaprio J, Ripatti S, Daly M, Palotie A. Saarentaus EC, et al. Among authors: ruotsalainen s. Mol Psychiatry. 2021 Sep;26(9):4884-4895. doi: 10.1038/s41380-021-01026-z. Epub 2021 Feb 1. Mol Psychiatry. 2021. PMID: 33526825 Free PMC article.
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection.
Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Wang C, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Bhattacharya R, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, Kiryluk K, Neale B, Ionita-Laza I, Engels EA, Brown DW, Smoller JW, Green R, Karlson EW, Lebo M, Ellinor PT, Weiss ST, Daly MJ; Biobank Japan Project; FinnGen Consortium; Terao C, Zhao H, Ebert BL, Reilly MP, Ganna A, Machiela MJ, Genovese G, Natarajan P. Zekavat SM, et al. Nat Med. 2021 Jun;27(6):1012-1024. doi: 10.1038/s41591-021-01371-0. Epub 2021 Jun 7. Nat Med. 2021. PMID: 34099924 Free PMC article.
How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study.
Widén E, Junna N, Ruotsalainen S, Surakka I, Mars N, Ripatti P, Partanen JJ, Aro J, Mustonen P, Tuomi T, Palotie A, Salomaa V, Kaprio J, Partanen J, Hotakainen K, Pöllänen P, Ripatti S. Widén E, et al. Among authors: ruotsalainen s. Circ Genom Precis Med. 2022 Apr;15(2):e003459. doi: 10.1161/CIRCGEN.121.003459. Epub 2022 Feb 7. Circ Genom Precis Med. 2022. PMID: 35130028 Free article.
88 results