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Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes.
Oncogene. 2016 May 12;35(19):2413-27. doi: 10.1038/onc.2015.318. Epub 2015 Aug 24.
Oncogene. 2016.
PMID: 26300000
Review.
Facilitates chromatin transcription complex is an "accelerator" of tumor transformation and potential marker and target of aggressive cancers.
Garcia H, Miecznikowski JC, Safina A, Commane M, Ruusulehto A, Kilpinen S, Leach RW, Attwood K, Li Y, Degan S, Omilian AR, Guryanova O, Papantonopoulou O, Wang J, Buck M, Liu S, Morrison C, Gurova KV.
Garcia H, et al. Among authors: ruusulehto a.
Cell Rep. 2013 Jul 11;4(1):159-73. doi: 10.1016/j.celrep.2013.06.013. Epub 2013 Jul 3.
Cell Rep. 2013.
PMID: 23831030
Free PMC article.
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Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers.
Drilon A, Somwar R, Mangatt BP, Edgren H, Desmeules P, Ruusulehto A, Smith RS, Delasos L, Vojnic M, Plodkowski AJ, Sabari J, Ng K, Montecalvo J, Chang J, Tai H, Lockwood WW, Martinez V, Riely GJ, Rudin CM, Kris MG, Arcila ME, Matheny C, Benayed R, Rekhtman N, Ladanyi M, Ganji G.
Drilon A, et al. Among authors: ruusulehto a.
Cancer Discov. 2018 Jun;8(6):686-695. doi: 10.1158/2159-8290.CD-17-1004. Epub 2018 Apr 2.
Cancer Discov. 2018.
PMID: 29610121
Free PMC article.
Clinical Trial.
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