S10-RR20939/RR/NCRR NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	1
2008	3
2009	3
2010	3
2011	1
2012	1
2013	3
2014	4
2015	2
2016	1
2024	0

1

The LonA Protease Regulates Biofilm Formation, Motility, Virulence, and the Type VI Secretion System in Vibrio cholerae.

Rogers A, Townsley L, Gallego-Hernandez AL, Beyhan S, Kwuan L, Yildiz FH. Rogers A, et al. J Bacteriol. 2016 Jan 11;198(6):973-85. doi: 10.1128/JB.00741-15. J Bacteriol. 2016. PMID: 26755629 Free PMC article.

2

A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors.

Jameson JB 2nd, Kenyon V, Holman TR. Jameson JB 2nd, et al. Anal Biochem. 2015 May 1;476:45-50. doi: 10.1016/j.ab.2015.02.011. Epub 2015 Feb 21. Anal Biochem. 2015. PMID: 25712042 Free PMC article.

3

Temperature affects c-di-GMP signalling and biofilm formation in Vibrio cholerae.

Townsley L, Yildiz FH. Townsley L, et al. Environ Microbiol. 2015 Nov;17(11):4290-305. doi: 10.1111/1462-2920.12799. Epub 2015 Mar 25. Environ Microbiol. 2015. PMID: 25684220 Free PMC article.

4

A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2.

Jameson JB 2nd, Kantz A, Schultz L, Kalyanaraman C, Jacobson MP, Maloney DJ, Jadhav A, Simeonov A, Holman TR. Jameson JB 2nd, et al. PLoS One. 2014 Aug 11;9(8):e104094. doi: 10.1371/journal.pone.0104094. eCollection 2014. PLoS One. 2014. PMID: 25111178 Free PMC article.

5

ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid.

Smyrniotis CJ, Barbour SR, Xia Z, Hixon MS, Holman TR. Smyrniotis CJ, et al. Biochemistry. 2014 Jul 15;53(27):4407-19. doi: 10.1021/bi401621d. Epub 2014 Jul 2. Biochemistry. 2014. PMID: 24893149 Free PMC article.

6

Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.

Rai G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, Holman TR. Rai G, et al. J Med Chem. 2014 May 22;57(10):4035-48. doi: 10.1021/jm401915r. Epub 2014 May 13. J Med Chem. 2014. PMID: 24684213 Free PMC article.

7

Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.

Luci DK, Jameson JB 2nd, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, Jadhav A, Simeonov A, Holman TR, Maloney DJ. Luci DK, et al. J Med Chem. 2014 Jan 23;57(2):495-506. doi: 10.1021/jm4016476. Epub 2014 Jan 6. J Med Chem. 2014. PMID: 24393039 Free PMC article.

8

Kinetic and structural investigations into the allosteric and pH effect on the substrate specificity of human epithelial 15-lipoxygenase-2.

Joshi N, Hoobler EK, Perry S, Diaz G, Fox B, Holman TR. Joshi N, et al. Biochemistry. 2013 Nov 12;52(45):8026-35. doi: 10.1021/bi4010649. Epub 2013 Oct 30. Biochemistry. 2013. PMID: 24171444 Free PMC article.

9

Discovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapy.

Hoobler EK, Rai G, Warrilow AG, Perry SC, Smyrniotis CJ, Jadhav A, Simeonov A, Parker JE, Kelly DE, Maloney DJ, Kelly SL, Holman TR. Hoobler EK, et al. PLoS One. 2013 Jun 24;8(6):e65928. doi: 10.1371/journal.pone.0065928. Print 2013. PLoS One. 2013. PMID: 23826084 Free PMC article.

10

The transcriptional regulator, CosR, controls compatible solute biosynthesis and transport, motility and biofilm formation in Vibrio cholerae.

Shikuma NJ, Davis KR, Fong JN, Yildiz FH. Shikuma NJ, et al. Environ Microbiol. 2013 May;15(5):1387-99. doi: 10.1111/j.1462-2920.2012.02805.x. Epub 2012 Jun 12. Environ Microbiol. 2013. PMID: 22690884 Free PMC article.

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