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HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia.
Kontro M, Kumar A, Majumder MM, Eldfors S, Parsons A, Pemovska T, Saarela J, Yadav B, Malani D, Fløisand Y, Höglund M, Remes K, Gjertsen BT, Kallioniemi O, Wennerberg K, Heckman CA, Porkka K. Kontro M, et al. Among authors: saarela j. Leukemia. 2017 Feb;31(2):301-309. doi: 10.1038/leu.2016.222. Epub 2016 Aug 8. Leukemia. 2017. PMID: 27499136
Suppression of BRCA1 sensitizes cells to proteasome inhibitors.
Gu Y, Bouwman P, Greco D, Saarela J, Yadav B, Jonkers J, Kuznetsov SG. Gu Y, et al. Among authors: saarela j. Cell Death Dis. 2014 Dec 18;5(12):e1580. doi: 10.1038/cddis.2014.537. Cell Death Dis. 2014. PMID: 25522274 Free PMC article.
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.
Pokharel YR, Saarela J, Szwajda A, Rupp C, Rokka A, Lal Kumar Karna S, Teittinen K, Corthals G, Kallioniemi O, Wennerberg K, Aittokallio T, Westermarck J. Pokharel YR, et al. Among authors: saarela j. Mol Cell Proteomics. 2015 Dec;14(12):3274-83. doi: 10.1074/mcp.M115.050773. Epub 2015 Oct 23. Mol Cell Proteomics. 2015. PMID: 26499835 Free PMC article.
Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis.
Savola P, Kelkka T, Rajala HL, Kuuliala A, Kuuliala K, Eldfors S, Ellonen P, Lagström S, Lepistö M, Hannunen T, Andersson EI, Khajuria RK, Jaatinen T, Koivuniemi R, Repo H, Saarela J, Porkka K, Leirisalo-Repo M, Mustjoki S. Savola P, et al. Among authors: saarela j. Nat Commun. 2017 Jun 21;8:15869. doi: 10.1038/ncomms15869. Nat Commun. 2017. PMID: 28635960 Free PMC article.
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer.
Tang J, Gautam P, Gupta A, He L, Timonen S, Akimov Y, Wang W, Szwajda A, Jaiswal A, Turei D, Yadav B, Kankainen M, Saarela J, Saez-Rodriguez J, Wennerberg K, Aittokallio T. Tang J, et al. Among authors: saarela j. NPJ Syst Biol Appl. 2019 Jul 8;5:20. doi: 10.1038/s41540-019-0098-z. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31312514 Free PMC article.
276 results