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Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.
Hancock DB, Guo Y, Reginsson GW, Gaddis NC, Lutz SM, Sherva R, Loukola A, Minica CC, Markunas CA, Han Y, Young KA, Gudbjartsson DF, Gu F, McNeil DW, Qaiser B, Glasheen C, Olson S, Landi MT, Madden PAF, Farrer LA, Vink J, Saccone NL, Neale MC, Kranzler HR, McKay J, Hung RJ, Amos CI, Marazita ML, Boomsma DI, Baker TB, Gelernter J, Kaprio J, Caporaso NE, Thorgeirsson TE, Hokanson JE, Bierut LJ, Stefansson K, Johnson EO. Hancock DB, et al. Among authors: saccone nl. Mol Psychiatry. 2018 Sep;23(9):1911-1919. doi: 10.1038/mp.2017.193. Epub 2017 Oct 3. Mol Psychiatry. 2018. PMID: 28972577 Free PMC article.
A clustering approach for localizing disease susceptibility loci.
Neuman RJ, Bierut LJ, Rasmussen E, Saccone NL, Rice JP, Corbett J, Sun L, Liu KY. Neuman RJ, et al. Among authors: saccone nl. Genet Epidemiol. 2001;21 Suppl 1:S534-9. doi: 10.1002/gepi.2001.21.s1.s534. Genet Epidemiol. 2001. PMID: 11793732
A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9.
Dick DM, Aliev F, Wang JC, Saccone S, Hinrichs A, Bertelsen S, Budde J, Saccone N, Foroud T, Nurnberger J Jr, Xuei X, Conneally PM, Schuckit M, Almasy L, Crowe R, Kuperman S, Kramer J, Tischfield JA, Hesselbrock V, Edenberg HJ, Porjesz B, Rice JP, Bierut L, Goate A. Dick DM, et al. Biol Psychiatry. 2008 Jun 1;63(11):1047-53. doi: 10.1016/j.biopsych.2007.11.005. Epub 2007 Dec 27. Biol Psychiatry. 2008. PMID: 18163977 Free PMC article.
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP, Fox L, Goldstein E, Reyes O, Saccone N, Saccone S, Xuei X, Bucholz K, Kuperman S, Nurnberger J Jr, Rice JP, Schuckit M, Tischfield J, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate AM. Wang JC, et al. Mol Psychiatry. 2009 May;14(5):501-10. doi: 10.1038/mp.2008.42. Epub 2008 Apr 15. Mol Psychiatry. 2009. PMID: 18414406 Free PMC article.
Common polymorphisms in FMO1 are associated with nicotine dependence.
Hinrichs AL, Murphy SE, Wang JC, Saccone S, Saccone N, Steinbach JH, Goate A, Stevens VL, Bierut LJ. Hinrichs AL, et al. Pharmacogenet Genomics. 2011 Jul;21(7):397-402. doi: 10.1097/FPC.0b013e328346886f. Pharmacogenet Genomics. 2011. PMID: 21540762 Free PMC article.
ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.
Bierut LJ, Goate AM, Breslau N, Johnson EO, Bertelsen S, Fox L, Agrawal A, Bucholz KK, Grucza R, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Porjesz B, Saccone NL, Schuckit M, Tischfield J, Wang JC, Foroud T, Rice JP, Edenberg HJ. Bierut LJ, et al. Among authors: saccone nl. Mol Psychiatry. 2012 Apr;17(4):445-50. doi: 10.1038/mp.2011.124. Epub 2011 Oct 4. Mol Psychiatry. 2012. PMID: 21968928 Free PMC article.
CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results.
Rice JP, Hartz SM, Agrawal A, Almasy L, Bennett S, Breslau N, Bucholz KK, Doheny KF, Edenberg HJ, Goate AM, Hesselbrock V, Howells WB, Johnson EO, Kramer J, Krueger RF, Kuperman S, Laurie C, Manolio TA, Neuman RJ, Nurnberger JI, Porjesz B, Pugh E, Ramos EM, Saccone N, Saccone S, Schuckit M, Bierut LJ; GENEVA Consortium. Rice JP, et al. Addiction. 2012 Nov;107(11):2019-28. doi: 10.1111/j.1360-0443.2012.03922.x. Epub 2012 Jun 15. Addiction. 2012. PMID: 22524403 Free PMC article.
141 results