Sachs K - Search Results

1

Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators.

Bodenmiller B, Zunder ER, Finck R, Chen TJ, Savig ES, Bruggner RV, Simonds EF, Bendall SC, Sachs K, Krutzik PO, Nolan GP. Bodenmiller B, et al. Among authors: sachs k. Nat Biotechnol. 2012 Sep;30(9):858-67. doi: 10.1038/nbt.2317. Nat Biotechnol. 2012. PMID: 22902532 Free PMC article.

2

Causal protein-signaling networks derived from multiparameter single-cell data.

Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Sachs K, et al. Science. 2005 Apr 22;308(5721):523-9. doi: 10.1126/science.1105809. Science. 2005. PMID: 15845847

3

Learning signaling network structures with sparsely distributed data.

Sachs K, Itani S, Carlisle J, Nolan GP, Pe'er D, Lauffenburger DA. Sachs K, et al. J Comput Biol. 2009 Feb;16(2):201-12. doi: 10.1089/cmb.2008.07TT. J Comput Biol. 2009. PMID: 19193145 Free PMC article.

4

Learning cyclic signaling pathway structures while minimizing data requirements.

Sachs K, Itani S, Fitzgerald J, Wille L, Schoeberl B, Dahleh MA, Nolan GP. Sachs K, et al. Pac Symp Biocomput. 2009:63-74. doi: 10.1142/9789812836939_0007. Pac Symp Biocomput. 2009. PMID: 19209696 Free PMC article.

5

Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes.

Sachs K, Gentles AJ, Youland R, Itani S, Irish J, Nolan GP, Plevritis SK. Sachs K, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:6624-7. doi: 10.1109/IEMBS.2009.5332563. Annu Int Conf IEEE Eng Med Biol Soc. 2009. PMID: 19963681 Free PMC article.

6

Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.

Gibbs KD Jr, Gilbert PM, Sachs K, Zhao F, Blau HM, Weissman IL, Nolan GP, Majeti R. Gibbs KD Jr, et al. Among authors: sachs k. Blood. 2011 Apr 21;117(16):4226-33. doi: 10.1182/blood-2010-07-298232. Epub 2011 Feb 28. Blood. 2011. PMID: 21357764 Free PMC article.

7

Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.

Bendall SC, Simonds EF, Qiu P, Amir el-AD, Krutzik PO, Finck R, Bruggner RV, Melamed R, Trejo A, Ornatsky OI, Balderas RS, Plevritis SK, Sachs K, Pe'er D, Tanner SD, Nolan GP. Bendall SC, et al. Among authors: sachs k. Science. 2011 May 6;332(6030):687-96. doi: 10.1126/science.1198704. Science. 2011. PMID: 21551058 Free PMC article.

8

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE.

Qiu P, Simonds EF, Bendall SC, Gibbs KD Jr, Bruggner RV, Linderman MD, Sachs K, Nolan GP, Plevritis SK. Qiu P, et al. Among authors: sachs k. Nat Biotechnol. 2011 Oct 2;29(10):886-91. doi: 10.1038/nbt.1991. Nat Biotechnol. 2011. PMID: 21964415 Free PMC article.

9

Normalization of mass cytometry data with bead standards.

Finck R, Simonds EF, Jager A, Krishnaswamy S, Sachs K, Fantl W, Pe'er D, Nolan GP, Bendall SC. Finck R, et al. Among authors: sachs k. Cytometry A. 2013 May;83(5):483-94. doi: 10.1002/cyto.a.22271. Epub 2013 Mar 19. Cytometry A. 2013. PMID: 23512433 Free PMC article.

10

Single timepoint models of dynamic systems.

Sachs K, Itani S, Fitzgerald J, Schoeberl B, Nolan GP, Tomlin CJ. Sachs K, et al. Interface Focus. 2013 Aug 6;3(4):20130019. doi: 10.1098/rsfs.2013.0019. Interface Focus. 2013. PMID: 24511382 Free PMC article.

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