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Page 1
The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians.
Sun H, Lin M, Russell EM, Minster RL, Chan TF, Dinh BL, Naseri T, Reupena MS, Lum-Jones A; Samoan Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group; Cheng I, Wilkens LR, Le Marchand L, Haiman CA, Chiang CWK. Sun H, et al. PLoS Genet. 2021 Feb 11;17(2):e1009273. doi: 10.1371/journal.pgen.1009273. eCollection 2021 Feb. PLoS Genet. 2021. PMID: 33571193 Free PMC article.
Epidemiological studies of obesity, Type-2 diabetes (T2D), cardiovascular diseases and several common cancers have revealed an increased risk in Native Hawaiians compared to European- or Asian-Americans living in the Hawaiian islands. ...In conclusion, we showed that Polyn …
Epidemiological studies of obesity, Type-2 diabetes (T2D), cardiovascular diseases and several common cancers have revealed an increa …
ECHS1 disease in two unrelated families of Samoan descent: Common variant - rare disorder.
Simon MT, Eftekharian SS, Ferdinandusse S, Tang S, Naseri T, Reupena MS, McGarvey ST, Minster RL, Weeks DE; Samoan Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group; Nguyen DD, Lee S, Ellsworth KA, Vaz FM, Dimmock D, Pitt J, Abdenur JE. Simon MT, et al. Am J Med Genet A. 2021 Jan;185(1):157-167. doi: 10.1002/ajmg.a.61936. Epub 2020 Oct 28. Am J Med Genet A. 2021. PMID: 33112498 Free PMC article.
We present clinical, biochemical, molecular, and functional data for four affected patients from two unrelated families of Samoan descent with identical novel compound heterozygous mutations. ...Additional investigations at the DNA (aCGH, WGS) and RNA (qPCR, RT-PCR, RNA-Se …
We present clinical, biochemical, molecular, and functional data for four affected patients from two unrelated families of Samoan des …