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The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment.
Cell Mol Immunol. 2020 Jun;17(6):653-655. doi: 10.1038/s41423-020-0406-y. Epub 2020 Mar 24.
Cell Mol Immunol. 2020.
PMID: 32210393
Free PMC article.
No abstract available.
Placental disposition of eculizumab, C5 and C5-eculizumab in two pregnancies of a woman with paroxysmal nocturnal haemoglobinuria.
Eliesen GAM, van Drongelen J, van den Broek PHH, Sarlea A, van der Heijden OWH, Langemeijer S, Greupink R, Volokhina EB, Russel FGM.
Eliesen GAM, et al. Among authors: sarlea a.
Br J Clin Pharmacol. 2021 Apr;87(4):2128-2131. doi: 10.1111/bcp.14565. Epub 2020 Nov 2.
Br J Clin Pharmacol. 2021.
PMID: 32986871
Free PMC article.
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Potent induction of trained immunity by Saccharomyces cerevisiae β-glucans.
Vuscan P, Kischkel B, Hatzioannou A, Markaki E, Sarlea A, Tintoré M, Cuñé J, Verginis P, de Lecea C, Chavakis T, Joosten LAB, Netea MG.
Vuscan P, et al. Among authors: sarlea a.
Front Immunol. 2024 Feb 13;15:1323333. doi: 10.3389/fimmu.2024.1323333. eCollection 2024.
Front Immunol. 2024.
PMID: 38415247
Free PMC article.
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MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells.
Röring RJ, Debisarun PA, Botey-Bataller J, Suen TK, Bulut Ö, Kilic G, Koeken VA, Sarlea A, Bahrar H, Dijkstra H, Lemmers H, Gössling KL, Rüchel N, Ostermann PN, Müller L, Schaal H, Adams O, Borkhardt A, Ariyurek Y, de Meijer EJ, Kloet SL, Ten Oever J, Placek K, Li Y, Netea MG.
Röring RJ, et al. Among authors: sarlea a.
J Clin Invest. 2024 Jan 30;134(7):e170848. doi: 10.1172/JCI170848.
J Clin Invest. 2024.
PMID: 38290093
Free PMC article.
Clinical Trial.
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