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The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment.
van den Heuvel LP, van de Kar NCAJ, Duineveld C, Sarlea A, van der Velden TJAM, Liebrand WTB, van Kraaij S, Schjalm C, Bouwmeester R, Wetzels JFM, Mollnes TE, Volokhina EB. van den Heuvel LP, et al. Among authors: sarlea a. Cell Mol Immunol. 2020 Jun;17(6):653-655. doi: 10.1038/s41423-020-0406-y. Epub 2020 Mar 24. Cell Mol Immunol. 2020. PMID: 32210393 Free PMC article. No abstract available.
Potent induction of trained immunity by Saccharomyces cerevisiae β-glucans.
Vuscan P, Kischkel B, Hatzioannou A, Markaki E, Sarlea A, Tintoré M, Cuñé J, Verginis P, de Lecea C, Chavakis T, Joosten LAB, Netea MG. Vuscan P, et al. Among authors: sarlea a. Front Immunol. 2024 Feb 13;15:1323333. doi: 10.3389/fimmu.2024.1323333. eCollection 2024. Front Immunol. 2024. PMID: 38415247 Free PMC article.
MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells.
Röring RJ, Debisarun PA, Botey-Bataller J, Suen TK, Bulut Ö, Kilic G, Koeken VA, Sarlea A, Bahrar H, Dijkstra H, Lemmers H, Gössling KL, Rüchel N, Ostermann PN, Müller L, Schaal H, Adams O, Borkhardt A, Ariyurek Y, de Meijer EJ, Kloet SL, Ten Oever J, Placek K, Li Y, Netea MG. Röring RJ, et al. Among authors: sarlea a. J Clin Invest. 2024 Jan 30;134(7):e170848. doi: 10.1172/JCI170848. J Clin Invest. 2024. PMID: 38290093 Free PMC article. Clinical Trial.