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Synthesis of tri- or tetrasubstituted pyrimidine derivatives through the [5+1] annulation of enamidines with either N,N-dimethylformamide dialkyl acetals or orthoesters and their application in a ring transformation of pyrimidines to pyrido[2,3-d]pyrimidin-5-one derivatives.
Sasada T, Aoki Y, Ikeda R, Sakai N, Konakahara T. Sasada T, et al. Chemistry. 2011 Aug 16;17(34):9385-94. doi: 10.1002/chem.201100040. Epub 2011 Jul 20. Chemistry. 2011. PMID: 21780196
MMP1, IL-1β, sTNFR-1, and IL-6 are prognostic factors for patients with unresectable or metastatic renal cell carcinoma treated with immune checkpoint inhibitors.
Nagasaka H, Kishida T, Kouro T, Igarashi Y, Takebe S, Yamamoto S, Kondo T, Koizumi M, Terao H, Suzuki T, Nakaigawa N, Himuro H, Wei F, Sasada T. Nagasaka H, et al. Among authors: sasada t. Int J Clin Oncol. 2024 Apr 6. doi: 10.1007/s10147-024-02477-4. Online ahead of print. Int J Clin Oncol. 2024. PMID: 38580797
Circulating IL-6 and not its circulating signaling components sIL-6R and sgp130 demonstrate clinical significance in NSCLC patients treated with immune checkpoint inhibitors.
Nakahara Y, Kouro T, Motoyama S, Miura M, Fujita K, Igarashi Y, Higashijima N, Matsuo N, Himuro H, Wei F, Horaguchi S, Tsuji K, Mano Y, Komahashi M, Saito H, Azuma K, Sasada T. Nakahara Y, et al. Among authors: sasada t. Front Cell Dev Biol. 2024 Jan 16;11:1324898. doi: 10.3389/fcell.2023.1324898. eCollection 2023. Front Cell Dev Biol. 2024. PMID: 38469154 Free PMC article.
Enhancing Mass spectrometry-based tumor immunopeptide identification: machine learning filter leveraging HLA binding affinity, aliphatic index and retention time deviation.
Wei F, Kouro T, Nakamura Y, Ueda H, Iiizumi S, Hasegawa K, Asahina Y, Kishida T, Morinaga S, Himuro H, Horaguchi S, Tsuji K, Mano Y, Nakamura N, Kawamura T, Sasada T. Wei F, et al. Among authors: sasada t. Comput Struct Biotechnol J. 2024 Feb 3;23:859-869. doi: 10.1016/j.csbj.2024.01.023. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38356658 Free PMC article.
212 results