Sawyer EJ - Search Results

1

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Lambrechts D, Thienpont B, Neven P, Wildiers H, Broeks A, Van't Veer LJ, Th Rutgers EJ, Couch FJ, Olson JE, Hallberg E, Vachon C, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Peto J, Dos-Santos-Silva I, Gibson L, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Hall P, Li J, Liu J, Humphreys K, Kang D, Choi JY, Park SK, Noh DY, Matsuo K, Ito H, Iwata H, Yatabe Y, Guénel P, Truong T, Menegaux F, Sanchez M, Burwinkel B, Marme F, Schneeweiss A, Sohn C, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Benitez J, Zamora MP, Perez JI, Menéndez P, Shu XO, Lu W, Gao YT, Cai Q, Cox A, Cross SS, Reed MW, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Lindblom A, Margolin S, Teo SH, Yip CH, Lee DS, Wong TY, Hooning MJ, Martens JW, Collée JM, van Deurzen CH, Hopper JL, Southey MC, … See abstract for full author list ➔ Ghoussaini M, et al. Among authors: sawyer ej. Nat Commun. 2014 Sep 23;4:4999. doi: 10.1038/ncomms5999. Nat Commun. 2014. PMID: 25248036 Free PMC article.

2

Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.

Sawyer EJ, Hanby AM, Ellis P, Lakhani SR, Ellis IO, Boyle S, Tomlinson IP. Sawyer EJ, et al. Am J Pathol. 2000 Mar;156(3):1093-8. doi: 10.1016/S0002-9440(10)64977-2. Am J Pathol. 2000. PMID: 10702425 Free PMC article.

3

Malignant phyllodes tumours show stromal overexpression of c-myc and c-kit.

Sawyer EJ, Poulsom R, Hunt FT, Jeffery R, Elia G, Ellis IO, Ellis P, Tomlinson IP, Hanby AM. Sawyer EJ, et al. J Pathol. 2003 May;200(1):59-64. doi: 10.1002/path.1318. J Pathol. 2003. PMID: 12692842

4

An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome.

Jaeger EE, Woodford-Richens KL, Lockett M, Rowan AJ, Sawyer EJ, Heinimann K, Rozen P, Murday VA, Whitelaw SC, Ginsberg A, Atkin WS, Lynch HT, Southey MC, Debinski H, Eng C, Bodmer WF, Talbot IC, Hodgson SV, Thomas HJ, Tomlinson IP. Jaeger EE, et al. Among authors: sawyer ej. Am J Hum Genet. 2003 May;72(5):1261-7. doi: 10.1086/375144. Epub 2003 Apr 14. Am J Hum Genet. 2003. PMID: 12696020 Free PMC article.

5

Beta-catenin abnormalities and associated insulin-like growth factor overexpression are important in phyllodes tumours and fibroadenomas of the breast.

Sawyer EJ, Hanby AM, Poulsom R, Jeffery R, Gillett CE, Ellis IO, Ellis P, Tomlinson IP. Sawyer EJ, et al. J Pathol. 2003 Aug;200(5):627-32. doi: 10.1002/path.1391. J Pathol. 2003. PMID: 12898599

6

O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions.

Halford S, Rowan A, Sawyer E, Talbot I, Tomlinson I. Halford S, et al. Gut. 2005 Jun;54(6):797-802. doi: 10.1136/gut.2004.059535. Gut. 2005. PMID: 15888787 Free PMC article.

7

A comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence.

Jones AM, Mitter R, Springall R, Graham T, Winter E, Gillett C, Hanby AM, Tomlinson IP, Sawyer EJ; Phyllodes Tumour Consortium. Jones AM, et al. Among authors: sawyer ej. J Pathol. 2008 Apr;214(5):533-44. doi: 10.1002/path.2320. J Pathol. 2008. PMID: 18288784

8

mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours.

Jones AM, Mitter R, Poulsom R, Gillett C, Hanby AM, Tomlinson IP, Sawyer EJ; Phyllodes Tumour Consortium. Jones AM, et al. Among authors: sawyer ej. J Pathol. 2008 Dec;216(4):408-17. doi: 10.1002/path.2439. J Pathol. 2008. PMID: 18937276

9

Low penetrance breast cancer predisposition SNPs are site specific.

Mcinerney N, Colleran G, Rowan A, Walther A, Barclay E, Spain S, Jones AM, Tuohy S, Curran C, Miller N, Kerin M, Tomlinson I, Sawyer E. Mcinerney N, et al. Breast Cancer Res Treat. 2009 Sep;117(1):151-9. doi: 10.1007/s10549-008-0235-7. Epub 2008 Nov 13. Breast Cancer Res Treat. 2009. PMID: 19005751

10

The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer.

Colleran G, McInerney N, Rowan A, Barclay E, Jones AM, Curran C, Miller N, Kerin M, Tomlinson I, Sawyer E. Colleran G, et al. Breast Cancer Res Treat. 2010 Jan;119(2):437-42. doi: 10.1007/s10549-009-0395-0. Epub 2009 Apr 24. Breast Cancer Res Treat. 2010. PMID: 19390964

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