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Mapping and quantifying mammalian transcriptomes by RNA-Seq.
Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B. Mortazavi A, et al. Among authors: schaeffer l. Nat Methods. 2008 Jul;5(7):621-8. doi: 10.1038/nmeth.1226. Epub 2008 May 30. Nat Methods. 2008. PMID: 18516045
Scaffolding a Caenorhabditis nematode genome with RNA-seq.
Mortazavi A, Schwarz EM, Williams B, Schaeffer L, Antoshechkin I, Wold BJ, Sternberg PW. Mortazavi A, et al. Among authors: schaeffer l. Genome Res. 2010 Dec;20(12):1740-7. doi: 10.1101/gr.111021.110. Epub 2010 Oct 27. Genome Res. 2010. PMID: 20980554 Free PMC article.
Updating RNA-Seq analyses after re-annotation.
Roberts A, Schaeffer L, Pachter L. Roberts A, et al. Among authors: schaeffer l. Bioinformatics. 2013 Jul 1;29(13):1631-7. doi: 10.1093/bioinformatics/btt197. Epub 2013 May 14. Bioinformatics. 2013. PMID: 23677943 Free PMC article.
Pseudoalignment for metagenomic read assignment.
Schaeffer L, Pimentel H, Bray N, Melsted P, Pachter L. Schaeffer L, et al. Bioinformatics. 2017 Jul 15;33(14):2082-2088. doi: 10.1093/bioinformatics/btx106. Bioinformatics. 2017. PMID: 28334086 Free PMC article.
Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells.
Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, Jaenisch R, Hockemeyer D. Forster R, et al. Among authors: schaeffer l. Stem Cell Reports. 2014 Jun 3;2(6):838-52. doi: 10.1016/j.stemcr.2014.05.001. eCollection 2014 Jun 3. Stem Cell Reports. 2014. PMID: 24936470 Free PMC article.
Early molecular events of autosomal-dominant Alzheimer's disease in marmosets with PSEN1 mutations.
Homanics GE, Park JE, Bailey L, Schaeffer DJ, Schaeffer L, He J, Li S, Zhang T, Haber A, Spruce C, Greenwood A, Murai T, Schultz L, Mongeau L, Ha SK, Oluoch J, Stein B, Choi SH, Huhe H, Thathiah A, Strick PL, Carter GW, Silva AC, Sukoff Rizzo SJ. Homanics GE, et al. Among authors: schaeffer l. Alzheimers Dement. 2024 Apr 4. doi: 10.1002/alz.13806. Online ahead of print. Alzheimers Dement. 2024. PMID: 38574388
H2A.Z is involved in premature aging and DSB repair initiation in muscle fibers.
Belotti E, Lacoste N, Iftikhar A, Simonet T, Papin C, Osseni A, Streichenberger N, Mari PO, Girard E, Graies M, Giglia-Mari G, Dimitrov S, Hamiche A, Schaeffer L. Belotti E, et al. Among authors: schaeffer l. Nucleic Acids Res. 2024 Apr 12;52(6):3031-3049. doi: 10.1093/nar/gkae020. Nucleic Acids Res. 2024. PMID: 38281187 Free PMC article.
352 results