Schmidt CF - Search Results

1

The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function.

Pfeffer TJ, Sasse F, Schmidt CF, Lakämper S, Kirschning A, Scholz T. Pfeffer TJ, et al. Among authors: schmidt cf. Eur J Med Chem. 2016 Apr 13;112:164-170. doi: 10.1016/j.ejmech.2016.02.022. Epub 2016 Feb 8. Eur J Med Chem. 2016. PMID: 26896705

2

Load-dependent release limits the processive stepping of the tetrameric Eg5 motor.

Korneev MJ, Lakämper S, Schmidt CF. Korneev MJ, et al. Among authors: schmidt cf. Eur Biophys J. 2007 Jul;36(6):675-81. doi: 10.1007/s00249-007-0134-6. Epub 2007 Feb 28. Eur Biophys J. 2007. PMID: 17333163 Free PMC article.

3

The effect of monastrol on the processive motility of a dimeric kinesin-5 head/kinesin-1 stalk chimera.

Lakämper S, Thiede C, Düselder A, Reiter S, Korneev MJ, Kapitein LC, Peterman EJ, Schmidt CF. Lakämper S, et al. Among authors: schmidt cf. J Mol Biol. 2010 May 28;399(1):1-8. doi: 10.1016/j.jmb.2010.03.009. Epub 2010 Mar 19. J Mol Biol. 2010. PMID: 20227420

4

Directionality of individual kinesin-5 Cin8 motors is modulated by loop 8, ionic strength and microtubule geometry.

Gerson-Gurwitz A, Thiede C, Movshovich N, Fridman V, Podolskaya M, Danieli T, Lakämper S, Klopfenstein DR, Schmidt CF, Gheber L. Gerson-Gurwitz A, et al. Among authors: schmidt cf. EMBO J. 2011 Nov 18;30(24):4942-54. doi: 10.1038/emboj.2011.403. EMBO J. 2011. PMID: 22101328 Free PMC article.

5

Neck-linker length dependence of processive Kinesin-5 motility.

Düselder A, Thiede C, Schmidt CF, Lakämper S. Düselder A, et al. Among authors: schmidt cf. J Mol Biol. 2012 Oct 19;423(2):159-68. doi: 10.1016/j.jmb.2012.06.043. Epub 2012 Jul 9. J Mol Biol. 2012. PMID: 22789568

6

A chimeric kinesin-1 head/kinesin-5 tail motor switches between diffusive and processive motility.

Thiede C, Lakämper S, Wessel AD, Kramer S, Schmidt CF. Thiede C, et al. Among authors: schmidt cf. Biophys J. 2013 Jan 22;104(2):432-41. doi: 10.1016/j.bpj.2012.11.3810. Biophys J. 2013. PMID: 23442865 Free PMC article.

7

Kinesin-5 Kip1 is a bi-directional motor that stabilizes microtubules and tracks their plus-ends in vivo.

Fridman V, Gerson-Gurwitz A, Shapira O, Movshovich N, Lakämper S, Schmidt CF, Gheber L. Fridman V, et al. Among authors: schmidt cf. J Cell Sci. 2013 Sep 15;126(Pt 18):4147-59. doi: 10.1242/jcs.125153. Epub 2013 Jul 18. J Cell Sci. 2013. PMID: 23868978

8

Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality.

Düselder A, Fridman V, Thiede C, Wiesbaum A, Goldstein A, Klopfenstein DR, Zaitseva O, Janson ME, Gheber L, Schmidt CF. Düselder A, et al. Among authors: schmidt cf. J Biol Chem. 2015 Jul 3;290(27):16841-50. doi: 10.1074/jbc.M114.620799. Epub 2015 May 19. J Biol Chem. 2015. PMID: 25991727 Free PMC article.

9

Allosteric inhibition of kinesin-5 modulates its processive directional motility.

Kwok BH, Kapitein LC, Kim JH, Peterman EJ, Schmidt CF, Kapoor TM. Kwok BH, et al. Among authors: schmidt cf. Nat Chem Biol. 2006 Sep;2(9):480-5. doi: 10.1038/nchembio812. Epub 2006 Aug 6. Nat Chem Biol. 2006. PMID: 16892050

10

A surprising twist.

Fakhri N, Schmidt CF. Fakhri N, et al. Among authors: schmidt cf. Elife. 2014 Apr 8;3:e02715. doi: 10.7554/eLife.02715. Elife. 2014. PMID: 24714499 Free PMC article.

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