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The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Among authors: schmidt re. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
Defective macrophage migration in Gαi2- but not Gαi3-deficient mice.
Wiege K, Le DD, Syed SN, Ali SR, Novakovic A, Beer-Hammer S, Piekorz RP, Schmidt RE, Nürnberg B, Gessner JE. Wiege K, et al. Among authors: schmidt re. J Immunol. 2012 Jul 15;189(2):980-7. doi: 10.4049/jimmunol.1200891. Epub 2012 Jun 15. J Immunol. 2012. PMID: 22706085
Gαi2 is the essential Gαi protein in immune complex-induced lung disease.
Wiege K, Ali SR, Gewecke B, Novakovic A, Konrad FM, Pexa K, Beer-Hammer S, Reutershan J, Piekorz RP, Schmidt RE, Nürnberg B, Gessner JE. Wiege K, et al. Among authors: schmidt re. J Immunol. 2013 Jan 1;190(1):324-33. doi: 10.4049/jimmunol.1201398. Epub 2012 Dec 5. J Immunol. 2013. PMID: 23225882
Orai1 controls C5a-induced neutrophil recruitment in inflammation.
Sogkas G, Vögtle T, Rau E, Gewecke B, Stegner D, Schmidt RE, Nieswandt B, Gessner JE. Sogkas G, et al. Among authors: schmidt re. Eur J Immunol. 2015 Jul;45(7):2143-53. doi: 10.1002/eji.201445337. Epub 2015 May 15. Eur J Immunol. 2015. PMID: 25912155 Free article.
867 results