Schreiber SL - Search Results

1

Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.

Seashore-Ludlow B, Rees MG, Cheah JH, Cokol M, Price EV, Coletti ME, Jones V, Bodycombe NE, Soule CK, Gould J, Alexander B, Li A, Montgomery P, Wawer MJ, Kuru N, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Bittker JA, Palmer M, Bradner JE, Shamji AF, Clemons PA, Schreiber SL. Seashore-Ludlow B, et al. Among authors: schreiber sl. Cancer Discov. 2015 Nov;5(11):1210-23. doi: 10.1158/2159-8290.CD-15-0235. Epub 2015 Oct 19. Cancer Discov. 2015. PMID: 26482930 Free PMC article.

2

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.

Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Hardwick JS, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70. doi: 10.1073/pnas.96.26.14866. Proc Natl Acad Sci U S A. 1999. PMID: 10611304 Free PMC article.

3

Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins.

Shamji AF, Kuruvilla FG, Schreiber SL. Shamji AF, et al. Among authors: schreiber sl. Curr Biol. 2000 Dec 14-28;10(24):1574-81. doi: 10.1016/s0960-9822(00)00866-6. Curr Biol. 2000. PMID: 11137008 Free article.

4

Exploiting site-site interactions on solid support to generate dimeric molecules.

Blackwell HE, Clemons PA, Schreiber SL. Blackwell HE, et al. Among authors: schreiber sl. Org Lett. 2001 Apr 19;3(8):1185-8. doi: 10.1021/ol015647i. Org Lett. 2001. PMID: 11348190

5

Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors.

Kuruvilla FG, Shamji AF, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7283-8. doi: 10.1073/pnas.121186898. Proc Natl Acad Sci U S A. 2001. PMID: 11416207 Free PMC article.

6

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

7

Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Clemons PA, Gladstone BG, Seth A, Chao ED, Foley MA, Schreiber SL. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2002 Jan;9(1):49-61. doi: 10.1016/s1074-5521(02)00085-6. Chem Biol. 2002. PMID: 11841938

8

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Nature. 2002 Apr 11;416(6881):653-7. doi: 10.1038/416653a. Nature. 2002. PMID: 11948353

9

Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.

Koehler AN, Shamji AF, Schreiber SL. Koehler AN, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 Jul 16;125(28):8420-1. doi: 10.1021/ja0352698. J Am Chem Soc. 2003. PMID: 12848532

10

Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations.

Haggarty SJ, Clemons PA, Schreiber SL. Haggarty SJ, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 Sep 3;125(35):10543-5. doi: 10.1021/ja035413p. J Am Chem Soc. 2003. PMID: 12940736

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