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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.
Sampaziotis F, de Brito MC, Madrigal P, Bertero A, Saeb-Parsy K, Soares FAC, Schrumpf E, Melum E, Karlsen TH, Bradley JA, Gelson WT, Davies S, Baker A, Kaser A, Alexander GJ, Hannan NRF, Vallier L. Sampaziotis F, et al. Among authors: schrumpf e. Nat Biotechnol. 2015 Aug;33(8):845-852. doi: 10.1038/nbt.3275. Epub 2015 Jul 13. Nat Biotechnol. 2015. PMID: 26167629 Free PMC article.
The biliary epithelium presents antigens to and activates natural killer T cells.
Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E. Schrumpf E, et al. Hepatology. 2015 Oct;62(4):1249-59. doi: 10.1002/hep.27840. Epub 2015 May 20. Hepatology. 2015. PMID: 25855031 Free PMC article.
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree.
Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E. Berntsen NL, et al. Among authors: schrumpf e. Am J Physiol Gastrointest Liver Physiol. 2018 Mar 1;314(3):G349-G359. doi: 10.1152/ajpgi.00124.2017. Epub 2017 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29212771 Free article.
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction.
Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A. Louwe MC, et al. Among authors: schrumpf e. JACC Basic Transl Sci. 2020 Dec 9;5(12):1210-1224. doi: 10.1016/j.jacbts.2020.09.013. eCollection 2020 Dec. JACC Basic Transl Sci. 2020. PMID: 33426377 Free PMC article.
HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
Zecher BF, Ellinghaus D, Schloer S, Niehrs A, Padoan B, Baumdick ME, Yuki Y, Martin MP, Glow D, Schröder-Schwarz J, Niersch J, Brias S, Müller LM, Habermann R, Kretschmer P, Früh T, Dänekas J, Wehmeyer MH, Poch T, Sebode M; International PSC Study Group (IPSCSG); Ellinghaus E, Degenhardt F, Körner C, Hoelzemer A, Fehse B, Oldhafer KJ, Schumacher U, Sauter G, Carrington M, Franke A, Bunders MJ, Schramm C, Altfeld M. Zecher BF, et al. Gut. 2024 Jan 5;73(2):325-337. doi: 10.1136/gutjnl-2023-329524. Gut. 2024. PMID: 37788895 Free PMC article.
257 results