Essential global role of CDC14 in DNA synthesis revealed by chromosome underreplication unrecognized by checkpoints in cdc14 mutants.
Dulev S, de Renty C, Mehta R, Minkov I, Schwob E, Strunnikov A.
Dulev S, et al. Among authors: schwob e.
Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14466-71. doi: 10.1073/pnas.0900190106. Epub 2009 Aug 7.
Proc Natl Acad Sci U S A. 2009.
PMID: 19666479
Free PMC article.
As the genome-wide slow-down of DNA replication does not trigger checkpoints [Lengronne A, Schwob E (2002) Mol Cell 9:1067-1078], CDC14 mutations pose an overwhelming challenge to genome stability, both generating chromosome damage and undermining the checkpoint con …
As the genome-wide slow-down of DNA replication does not trigger checkpoints [Lengronne A, Schwob E (2002) Mol Cell 9:1067-107 …