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Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P. Skarpengland T, et al. Among authors: segers fm. Sci Rep. 2016 Jun 22;6:28337. doi: 10.1038/srep28337. Sci Rep. 2016. PMID: 27328939 Free PMC article.
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA.
Skarpengland T, Dahl TB, Skjelland M, Scheffler K, de Sousa MML, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, Krohg-Sørensen K, Holm S, Bjørås M, Aukrust P, Halvorsen B. Skarpengland T, et al. Among authors: segers fm. Free Radic Biol Med. 2016 Aug;97:386-397. doi: 10.1016/j.freeradbiomed.2016.07.001. Epub 2016 Jul 2. Free Radic Biol Med. 2016. PMID: 27381496
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I. Kong XY, et al. Nucleic Acids Res. 2020 May 7;48(8):4463-4479. doi: 10.1093/nar/gkaa115. Nucleic Acids Res. 2020. PMID: 32083667 Free PMC article.
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation.
Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M. Yang M, et al. Cell Rep. 2020 Mar 24;30(12):4165-4178.e7. doi: 10.1016/j.celrep.2020.02.063. Cell Rep. 2020. PMID: 32209476 Free article.
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.
Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB, Holm S, Bennett MR, Aukrust P, Bjørås M, Halvorsen B. Quiles-Jiménez A, et al. Among authors: segers fm. Atherosclerosis. 2021 May;324:123-132. doi: 10.1016/j.atherosclerosis.2021.02.023. Epub 2021 Feb 23. Atherosclerosis. 2021. PMID: 33714552 Free article.
Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis.
Segers FME, Ruder AV, Westra MM, Lammers T, Dadfar SM, Roemhild K, Lam TS, Kooi ME, Cleutjens KBJM, Verheyen FK, Schurink GWH, Haenen GR, van Berkel TJC, Bot I, Halvorsen B, Sluimer JC, Biessen EAL. Segers FME, et al. Cardiovasc Res. 2023 Jan 18;118(17):3346-3359. doi: 10.1093/cvr/cvac032. Cardiovasc Res. 2023. PMID: 35325057 Free PMC article.
SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice.
Carracedo S, Lirussi L, Alsøe L, Segers F, Wang C, Bartosova Z, Bohov P, Tekin NB, Kong XY, Esbensen QY, Chen L, Wennerström A, Kroustallaki P, Ceolotto D, Tönjes A, Berge RK, Bruheim P, Wong G, Böttcher Y, Halvorsen B, Nilsen H. Carracedo S, et al. DNA Repair (Amst). 2022 Dec;120:103410. doi: 10.1016/j.dnarep.2022.103410. Epub 2022 Oct 3. DNA Repair (Amst). 2022. PMID: 36244177
17 results