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Abnormal metabolism of glycogen phosphate as a cause for Lafora disease.
Tagliabracci VS, Girard JM, Segvich D, Meyer C, Turnbull J, Zhao X, Minassian BA, Depaoli-Roach AA, Roach PJ. Tagliabracci VS, et al. J Biol Chem. 2008 Dec 5;283(49):33816-25. doi: 10.1074/jbc.M807428200. Epub 2008 Oct 13. J Biol Chem. 2008. PMID: 18852261 Free PMC article.
Incorporation of phosphate into glycogen by glycogen synthase.
Contreras CJ, Segvich DM, Mahalingan K, Chikwana VM, Kirley TL, Hurley TD, DePaoli-Roach AA, Roach PJ. Contreras CJ, et al. Among authors: segvich dm. Arch Biochem Biophys. 2016 May 1;597:21-9. doi: 10.1016/j.abb.2016.03.020. Epub 2016 Mar 29. Arch Biochem Biophys. 2016. PMID: 27036853 Free PMC article.
Novel method for detection of glycogen in cells.
Skurat AV, Segvich DM, DePaoli-Roach AA, Roach PJ. Skurat AV, et al. Among authors: segvich dm. Glycobiology. 2017 May 1;27(5):416-424. doi: 10.1093/glycob/cwx005. Glycobiology. 2017. PMID: 28077463 Free PMC article.
Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.
Tang B, Frasinyuk MS, Chikwana VM, Mahalingan KK, Morgan CA, Segvich DM, Bondarenko SP, Mrug GP, Wyrebek P, Watt DS, DePaoli-Roach AA, Roach PJ, Hurley TD. Tang B, et al. Among authors: segvich dm. J Med Chem. 2020 Apr 9;63(7):3538-3551. doi: 10.1021/acs.jmedchem.9b01851. Epub 2020 Mar 23. J Med Chem. 2020. PMID: 32134266 Free PMC article.
17 results