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A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network.
Cheng R, Fujinaga M, Yang J, Rong J, Haider A, Ogasawara D, Van RS, Shao T, Chen Z, Zhang X, Calderon Leon ER, Zhang Y, Mori W, Kumata K, Yamasaki T, Xie L, Sun S, Wang L, Ran C, Shao Y, Cravatt B, Josephson L, Zhang MR, Liang SH. Cheng R, et al. Among authors: shao t, shao y. Acta Pharmacol Sin. 2022 Nov;43(11):3002-3010. doi: 10.1038/s41401-022-00912-8. Epub 2022 May 5. Acta Pharmacol Sin. 2022. PMID: 35513432 Free PMC article.
Epitope alteration by small molecules and applications in drug discovery.
Zhu B, Yang J, Van R, Yang F, Yu Y, Yu A, Ran K, Yin K, Liang Y, Shen X, Yin W, Choi SH, Lu Y, Wang C, Shao Y, Shi L, Tanzi RE, Zhang C, Cheng Y, Zhang Z, Ran C. Zhu B, et al. Among authors: shao y. Chem Sci. 2022 Jun 28;13(27):8104-8116. doi: 10.1039/d2sc02819k. eCollection 2022 Jul 13. Chem Sci. 2022. PMID: 35919434 Free PMC article.
Assessment of cholesterol homeostasis in the living human brain.
Haider A, Zhao C, Wang L, Xiao Z, Rong J, Xia X, Chen Z, Pfister SK, Mast N, Yutuc E, Chen J, Li Y, Shao T, Warnock GI, Dawoud A, Connors TR, Oakley DH, Wei H, Wang J, Zheng Z, Xu H, Davenport AT, Daunais JB, Van RS, Shao Y, Wang Y, Zhang MR, Gebhard C, Pikuleva I, Levey AI, Griffiths WJ, Liang SH. Haider A, et al. Among authors: shao t, shao y. Sci Transl Med. 2022 Oct 5;14(665):eadc9967. doi: 10.1126/scitranslmed.adc9967. Epub 2022 Oct 5. Sci Transl Med. 2022. PMID: 36197966 Free PMC article.
Synthesis and Preliminary Evaluation of [11 C]GNE-1023 as a Potent PET Probe for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease.
Chen Z, Shao T, Gao W, Fu H, Collier TL, Rong J, Deng X, Yu Q, Zhang X, Davenport AT, Daunais JB, Wey HY, Shao Y, Josephson L, Qiu WW, Liang S. Chen Z, et al. Among authors: shao t, shao y. ChemMedChem. 2019 Sep 4;14(17):1580-1585. doi: 10.1002/cmdc.201900321. Epub 2019 Aug 22. ChemMedChem. 2019. PMID: 31365783 Free PMC article.
Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain.
Fu H, Tang W, Chen Z, Belov VV, Zhang G, Shao T, Zhang X, Yu Q, Rong J, Deng X, Han W, Myers SJ, Giffenig P, Wang L, Josephson L, Shao Y, Davenport AT, Daunais JB, Papisov M, Yuan H, Li Z, Traynelis SF, Liang SH. Fu H, et al. Among authors: shao t, shao y. ACS Chem Neurosci. 2019 May 15;10(5):2263-2275. doi: 10.1021/acschemneuro.8b00591. Epub 2019 Feb 27. ACS Chem Neurosci. 2019. PMID: 30698943 Free PMC article.
Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein.
Chen Z, Mori W, Zhang X, Yamasaki T, Dunn PJ, Zhang G, Fu H, Shao T, Zhang Y, Hatori A, Ma L, Fujinaga M, Xie L, Deng X, Li H, Yu Q, Rong J, Josephson L, Ma JA, Shao Y, Tomita S, Zhang MR, Liang SH. Chen Z, et al. Among authors: shao t, shao y. Eur J Med Chem. 2018 Sep 5;157:898-908. doi: 10.1016/j.ejmech.2018.08.019. Epub 2018 Aug 9. Eur J Med Chem. 2018. PMID: 30145376 Free PMC article.
Synthesis and Preliminary Evaluation of 11 C-Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype 4.
Deng X, Hatori A, Chen Z, Kumata K, Shao T, Zhang X, Yamasaki T, Hu K, Yu Q, Ma L, Wang G, Wang L, Shao Y, Josephson L, Sun S, Zhang MR, Liang S. Deng X, et al. Among authors: shao t, shao y. ChemMedChem. 2019 Feb 5;14(3):303-309. doi: 10.1002/cmdc.201800710. Epub 2018 Dec 27. ChemMedChem. 2019. PMID: 30589226
8,860 results