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Sulforaphane and its methylcarbonyl analogs inhibit the LPS-stimulated inflammatory response in human monocytes through modulating cytokine production, suppressing chemotactic migration and phagocytosis in a NF-κB- and MAPK-dependent manner.
Reddy SA, Shelar SB, Dang TM, Lee BN, Yang H, Ong SM, Ng HL, Chui WK, Wong SC, Chew EH. Reddy SA, et al. Among authors: shelar sb. Int Immunopharmacol. 2015 Feb;24(2):440-450. doi: 10.1016/j.intimp.2014.12.037. Epub 2015 Jan 10. Int Immunopharmacol. 2015. PMID: 25585231
Thioredoxin-dependent regulation of AIF-mediated DNA damage.
Shelar SB, Kaminska KK, Reddy SA, Kumar D, Tan CT, Yu VC, Lu J, Holmgren A, Hagen T, Chew EH. Shelar SB, et al. Free Radic Biol Med. 2015 Oct;87:125-36. doi: 10.1016/j.freeradbiomed.2015.06.029. Epub 2015 Jun 25. Free Radic Biol Med. 2015. PMID: 26119781
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Shelar S, Shim EH, Brinkley GJ, Kundu A, Carobbio F, Poston T, Tan J, Parekh V, Benson D, Crossman DK, Buckhaults PJ, Rakheja D, Kirkman R, Sato Y, Ogawa S, Dutta S, Velu SE, Emberley E, Pan A, Chen J, Huang T, Absher D, Becker A, Kunick C, Sudarshan S. Shelar S, et al. Clin Cancer Res. 2018 Dec 15;24(24):6433-6446. doi: 10.1158/1078-0432.CCR-18-1727. Epub 2018 Aug 14. Clin Cancer Res. 2018. PMID: 30108105 Free PMC article.
PRDM16 suppresses HIF-targeted gene expression in kidney cancer.
Kundu A, Nam H, Shelar S, Chandrashekar DS, Brinkley G, Karki S, Mitchell T, Livi CB, Buckhaults P, Kirkman R, Tang Y, Rowe GC, Wei S, Varambally S, Sudarshan S. Kundu A, et al. J Exp Med. 2020 Jun 1;217(6):e20191005. doi: 10.1084/jem.20191005. J Exp Med. 2020. PMID: 32251515 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33485564
23 results