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Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation.
Hum Mol Genet. 2015 Dec 15;24(24):6886-98. doi: 10.1093/hmg/ddv389. Epub 2015 Sep 18.
Hum Mol Genet. 2015.
PMID: 26385636
Free PMC article.
Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.
Coyne AN, Siddegowda BB, Estes PS, Johannesmeyer J, Kovalik T, Daniel SG, Pearson A, Bowser R, Zarnescu DC.
Coyne AN, et al. Among authors: siddegowda bb.
J Neurosci. 2014 Nov 26;34(48):15962-74. doi: 10.1523/JNEUROSCI.2526-14.2014.
J Neurosci. 2014.
PMID: 25429138
Free PMC article.
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TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6.
Lehmkuhl EM, Loganathan S, Alsop E, Blythe AD, Kovalik T, Mortimore NP, Barrameda D, Kueth C, Eck RJ, Siddegowda BB, Joardar A, Ball H, Macias ME, Bowser R, Van Keuren-Jensen K, Zarnescu DC.
Lehmkuhl EM, et al. Among authors: siddegowda bb.
Acta Neuropathol Commun. 2021 Mar 24;9(1):52. doi: 10.1186/s40478-021-01148-z.
Acta Neuropathol Commun. 2021.
PMID: 33762006
Free PMC article.
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