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Splice-switching as cancer therapy.
Jbara A, Siegfried Z, Karni R. Jbara A, et al. Among authors: siegfried z. Curr Opin Pharmacol. 2021 Aug;59:140-148. doi: 10.1016/j.coph.2021.05.008. Epub 2021 Jul 1. Curr Opin Pharmacol. 2021. PMID: 34217945 Review.
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair.
Amar-Schwartz A, Ben Hur V, Jbara A, Cohen Y, Barnabas GD, Arbib E, Siegfried Z, Mashahreh B, Hassouna F, Shilo A, Abu-Odeh M, Berger M, Wiener R, Aqeilan R, Geiger T, Karni R. Amar-Schwartz A, et al. Among authors: siegfried z. Elife. 2022 Oct 3;11:e79128. doi: 10.7554/eLife.79128. Elife. 2022. PMID: 36189922 Free PMC article.
Targeting splicing factors for cancer therapy.
Bashari A, Siegfried Z, Karni R. Bashari A, et al. Among authors: siegfried z. RNA. 2023 Apr;29(4):506-515. doi: 10.1261/rna.079585.123. Epub 2023 Jan 25. RNA. 2023. PMID: 36697261 Free PMC article.
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.
Jbara A, Lin KT, Stossel C, Siegfried Z, Shqerat H, Amar-Schwartz A, Elyada E, Mogilevsky M, Raitses-Gurevich M, Johnson JL, Yaron TM, Ovadia O, Jang GH, Danan-Gotthold M, Cantley LC, Levanon EY, Gallinger S, Krainer AR, Golan T, Karni R. Jbara A, et al. Among authors: siegfried z. Nature. 2023 May;617(7959):147-153. doi: 10.1038/s41586-023-05820-3. Epub 2023 Mar 22. Nature. 2023. PMID: 36949200 Free PMC article.
33 results