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Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz.
Keele BF, Jones JH, Terio KA, Estes JD, Rudicell RS, Wilson ML, Li Y, Learn GH, Beasley TM, Schumacher-Stankey J, Wroblewski E, Mosser A, Raphael J, Kamenya S, Lonsdorf EV, Travis DA, Mlengeya T, Kinsel MJ, Else JG, Silvestri G, Goodall J, Sharp PM, Shaw GM, Pusey AE, Hahn BH. Keele BF, et al. Among authors: silvestri g. Nature. 2009 Jul 23;460(7254):515-9. doi: 10.1038/nature08200. Nature. 2009. PMID: 19626114 Free PMC article.
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F. Schindler M, et al. Among authors: silvestri g. Cell. 2006 Jun 16;125(6):1055-67. doi: 10.1016/j.cell.2006.04.033. Cell. 2006. PMID: 16777597 Free article.
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, Perelson AS, Feinberg MB, Silvestri G. Gordon SN, et al. Among authors: silvestri g. J Virol. 2008 Apr;82(7):3725-35. doi: 10.1128/JVI.02408-07. Epub 2008 Jan 23. J Virol. 2008. PMID: 18216113 Free PMC article.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, Estes JD, Silvestri G, Ansari AA. Klatt NR, et al. Among authors: silvestri g. J Clin Invest. 2008 Jun;118(6):2039-49. doi: 10.1172/JCI33814. J Clin Invest. 2008. PMID: 18497876 Free PMC article.
Enhancing SIV-specific immunity in vivo by PD-1 blockade.
Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L, Vanderford TH, Chennareddi L, Silvestri G, Freeman GJ, Ahmed R, Amara RR. Velu V, et al. Among authors: silvestri g. Nature. 2009 Mar 12;458(7235):206-10. doi: 10.1038/nature07662. Epub 2008 Dec 10. Nature. 2009. PMID: 19078956 Free PMC article.
1,047 results