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Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment.
Court F, Tayama C, Romanelli V, Martin-Trujillo A, Iglesias-Platas I, Okamura K, Sugahara N, Simón C, Moore H, Harness JV, Keirstead H, Sanchez-Mut JV, Kaneki E, Lapunzina P, Soejima H, Wake N, Esteller M, Ogata T, Hata K, Nakabayashi K, Monk D. Court F, et al. Among authors: simon c. Genome Res. 2014 Apr;24(4):554-69. doi: 10.1101/gr.164913.113. Epub 2014 Jan 8. Genome Res. 2014. PMID: 24402520 Free PMC article.
Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting.
Sanchez-Delgado M, Court F, Vidal E, Medrano J, Monteagudo-Sánchez A, Martin-Trujillo A, Tayama C, Iglesias-Platas I, Kondova I, Bontrop R, Poo-Llanillo ME, Marques-Bonet T, Nakabayashi K, Simón C, Monk D. Sanchez-Delgado M, et al. Among authors: simon c. PLoS Genet. 2016 Nov 11;12(11):e1006427. doi: 10.1371/journal.pgen.1006427. eCollection 2016 Nov. PLoS Genet. 2016. PMID: 27835649 Free PMC article.
Characterization of parent-of-origin methylation using the Illumina Infinium MethylationEPIC array platform.
Hernandez Mora JR, Tayama C, Sánchez-Delgado M, Monteagudo-Sánchez A, Hata K, Ogata T, Medrano J, Poo-Llanillo ME, Simón C, Moran S, Esteller M, Tenorio J, Lapunzina P, Kagami M, Monk D, Nakabayashi K. Hernandez Mora JR, et al. Among authors: simon c. Epigenomics. 2018 Jul;10(7):941-954. doi: 10.2217/epi-2017-0172. Epub 2018 Jul 2. Epigenomics. 2018. PMID: 29962238
The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances.
Monteagudo-Sánchez A, Hernandez Mora JR, Simon C, Burton A, Tenorio J, Lapunzina P, Clark S, Esteller M, Kelsey G, López-Siguero JP, de Nanclares GP, Torres-Padilla ME, Monk D. Monteagudo-Sánchez A, et al. Among authors: simon c. Nucleic Acids Res. 2020 Nov 18;48(20):11394-11407. doi: 10.1093/nar/gkaa837. Nucleic Acids Res. 2020. PMID: 33053156 Free PMC article.
Single-cell multi-omic analysis profiles defective genome activation and epigenetic reprogramming associated with human pre-implantation embryo arrest.
Hernandez Mora JR, Buhigas C, Clark S, Del Gallego Bonilla R, Daskeviciute D, Monteagudo-Sánchez A, Poo-Llanillo ME, Medrano JV, Simón C, Meseguer M, Kelsey G, Monk D. Hernandez Mora JR, et al. Among authors: simon c. Cell Rep. 2023 Feb 28;42(2):112100. doi: 10.1016/j.celrep.2023.112100. Epub 2023 Feb 9. Cell Rep. 2023. PMID: 36763500 Free article.
Germ line development: lessons learned from pluripotent stem cells.
Martínez-Arroyo AM, Medrano JV, Remohí J, Simón C. Martínez-Arroyo AM, et al. Among authors: simon c. Curr Opin Genet Dev. 2014 Oct;28:64-70. doi: 10.1016/j.gde.2014.09.011. Epub 2014 Oct 14. Curr Opin Genet Dev. 2014. PMID: 25461452 Review.
Human embryo culture.
Mercader A, Valbuena D, Simón C. Mercader A, et al. Among authors: simon c. Methods Enzymol. 2006;420:3-18. doi: 10.1016/S0076-6879(06)20001-6. Methods Enzymol. 2006. PMID: 17161690
2,635 results