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Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cells.
Henrich FC, Singer K, Poller K, Bernhardt L, Strobl CD, Limm K, Ritter AP, Gottfried E, Völkl S, Jacobs B, Peter K, Mougiakakos D, Dettmer K, Oefner PJ, Bosserhoff AK, Kreutz MP, Aigner M, Mackensen A. Henrich FC, et al. Among authors: singer k. Oncoimmunology. 2016 Jun 10;5(8):e1184802. doi: 10.1080/2162402X.2016.1184802. eCollection 2016 Aug. Oncoimmunology. 2016. PMID: 27622058 Free PMC article.
Suppression of T-cell responses by tumor metabolites.
Singer K, Gottfried E, Kreutz M, Mackensen A. Singer K, et al. Cancer Immunol Immunother. 2011 Mar;60(3):425-31. doi: 10.1007/s00262-010-0967-1. Epub 2011 Jan 15. Cancer Immunol Immunother. 2011. PMID: 21240484 Free PMC article. Review.
New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.
Gottfried E, Lang SA, Renner K, Bosserhoff A, Gronwald W, Rehli M, Einhell S, Gedig I, Singer K, Seilbeck A, Mackensen A, Grauer O, Hau P, Dettmer K, Andreesen R, Oefner PJ, Kreutz M. Gottfried E, et al. Among authors: singer k. PLoS One. 2013 Jul 9;8(7):e66987. doi: 10.1371/journal.pone.0066987. Print 2013. PLoS One. 2013. PMID: 23874405 Free PMC article.
Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.
Renner K, Geiselhöringer AL, Fante M, Bruss C, Färber S, Schönhammer G, Peter K, Singer K, Andreesen R, Hoffmann P, Oefner P, Herr W, Kreutz M. Renner K, et al. Among authors: singer k. Eur J Immunol. 2015 Sep;45(9):2504-16. doi: 10.1002/eji.201545473. Epub 2015 Jul 20. Eur J Immunol. 2015. PMID: 26114249 Free article.
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Brand A, Singer K, Koehl GE, Kolitzus M, Schoenhammer G, Thiel A, Matos C, Bruss C, Klobuch S, Peter K, Kastenberger M, Bogdan C, Schleicher U, Mackensen A, Ullrich E, Fichtner-Feigl S, Kesselring R, Mack M, Ritter U, Schmid M, Blank C, Dettmer K, Oefner PJ, Hoffmann P, Walenta S, Geissler EK, Pouyssegur J, Villunger A, Steven A, Seliger B, Schreml S, Haferkamp S, Kohl E, Karrer S, Berneburg M, Herr W, Mueller-Klieser W, Renner K, Kreutz M. Brand A, et al. Among authors: singer k. Cell Metab. 2016 Nov 8;24(5):657-671. doi: 10.1016/j.cmet.2016.08.011. Epub 2016 Sep 15. Cell Metab. 2016. PMID: 27641098 Free article.
529 results