Singh SB - Search Results

1

Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy.

Singh SB, Jayasuriya H, Ondeyka JG, Herath KB, Zhang C, Zink DL, Tsou NN, Ball RG, Basilio A, Genilloud O, Diez MT, Vicente F, Pelaez F, Young K, Wang J. Singh SB, et al. J Am Chem Soc. 2006 Sep 13;128(36):11916-20. doi: 10.1021/ja062232p. J Am Chem Soc. 2006. PMID: 16953632

2

Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase.

Dufresne C, Wilson KE, Singh SB, Zink DL, Bergstrom JD, Rew D, Polishook JD, Meinz M, Huang L, Silverman KC, et al. Dufresne C, et al. Among authors: singh sb. J Nat Prod. 1993 Nov;56(11):1923-9. doi: 10.1021/np50101a009. J Nat Prod. 1993. PMID: 8289063

3

Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity.

Tsipouras A, Adefarati AA, Tkacz JS, Frazier EG, Rohrer SP, Birzin E, Rosegay A, Zink DL, Goetz MA, Singh SB, Schaeffer JM. Tsipouras A, et al. Among authors: singh sb. Bioorg Med Chem. 1996 Apr;4(4):531-6. doi: 10.1016/0968-0896(96)00036-3. Bioorg Med Chem. 1996. PMID: 8735840

4

Oreganic acid, a potent inhibitor of ras farnesyl-protein transferase.

Silverman KC, Jayasuriya H, Cascales C, Vilella D, Bills GF, Jenkins RG, Singh SB, Lingham RB. Silverman KC, et al. Among authors: singh sb. Biochem Biophys Res Commun. 1997 Mar 17;232(2):478-81. doi: 10.1006/bbrc.1997.6314. Biochem Biophys Res Commun. 1997. PMID: 9125205

5

Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.

Lingham RB, Silverman KC, Jayasuriya H, Kim BM, Amo SE, Wilson FR, Rew DJ, Schaber MD, Bergstrom JD, Koblan KS, Graham SL, Kohl NE, Gibbs JB, Singh SB. Lingham RB, et al. Among authors: singh sb. J Med Chem. 1998 Nov 5;41(23):4492-501. doi: 10.1021/jm980356+. J Med Chem. 1998. PMID: 9804689

6

Clavaric acid: a triterpenoid inhibitor of farnesyl-protein transferase from Clavariadelphus truncatus.

Jayasuriya H, Silverman KC, Zink DL, Jenkins RG, Sanchez M, Pelaez F, Vilella D, Lingham RB, Singh SB. Jayasuriya H, et al. Among authors: singh sb. J Nat Prod. 1998 Dec;61(12):1568-70. doi: 10.1021/np980200c. J Nat Prod. 1998. PMID: 9868169

7

Kampanols: novel Ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis.

Singh SB, Zink DL, Williams M, Polishook JD, Sanchez M, Silverman KC, Lingham RB. Singh SB, et al. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2071-6. doi: 10.1016/s0960-894x(98)00371-0. Bioorg Med Chem Lett. 1998. PMID: 9873488

8

Coprophilin: an anticoccidial agent produced by a dung inhabiting fungus.

Ondeyka JG, Giacobbe RA, Bills GF, Cuadrillero C, Schmatz D, Goetz MA, Zink DL, Singh SB. Ondeyka JG, et al. Among authors: singh sb. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3439-42. doi: 10.1016/s0960-894x(98)00629-5. Bioorg Med Chem Lett. 1998. PMID: 9934448

9

Efficient syntheses, human and yeast farnesyl-protein transferase inhibitory activities of chaetomellic acids and analogues.

Singh SB, Jayasuriya H, Silverman KC, Bonfiglio CA, Williamson JM, Lingham RB. Singh SB, et al. Bioorg Med Chem. 2000 Mar;8(3):571-80. doi: 10.1016/s0968-0896(99)00312-0. Bioorg Med Chem. 2000. PMID: 10732974

10

Inhibitors of farnesylation of Ras from a microbial natural products screening program.

Vilella D, Sánchez M, Platas G, Salazar O, Genilloud O, Royo I, Cascales C, Martín I, Díez T, Silverman KC, Lingham RB, Singh SB, Jayasuriya H, Peláez F. Vilella D, et al. Among authors: singh sb. J Ind Microbiol Biotechnol. 2000 Dec;25(6):315-327. doi: 10.1038/sj.jim.7000085. J Ind Microbiol Biotechnol. 2000. PMID: 11320419

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