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Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent.
Vashistha H, Marrero L, Reiss K, Cohen AJ, Malhotra A, Javed T, Bradley A, Abbruscato F, Giusti S, Jimenez A, Mehra S, Kaushal D, Giorgio M, Pelicci PG, Kakoki M, Singhal PC, Bunnell B, Meggs LG. Vashistha H, et al. Among authors: singhal pc. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1833-F1842. doi: 10.1152/ajprenal.00608.2017. Epub 2018 Sep 12. Am J Physiol Renal Physiol. 2018. PMID: 30207172 Free PMC article.
Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis.
Husain M, Meggs LG, Vashistha H, Simoes S, Griffiths KO, Kumar D, Mikulak J, Mathieson PW, Saleem MA, Del Valle L, Pina-Oviedo S, Wang JY, Seshan SV, Malhotra A, Reiss K, Singhal PC. Husain M, et al. Among authors: singhal pc. J Biol Chem. 2009 Jun 12;284(24):16648-16658. doi: 10.1074/jbc.M109.008482. Epub 2009 Apr 21. J Biol Chem. 2009. PMID: 19383602 Free PMC article.
Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.
Vashistha H, Singhal PC, Malhotra A, Husain M, Mathieson P, Saleem MA, Kuriakose C, Seshan S, Wilk A, Delvalle L, Peruzzi F, Giorgio M, Pelicci PG, Smithies O, Kim HS, Kakoki M, Reiss K, Meggs LG. Vashistha H, et al. Among authors: singhal pc. Am J Physiol Renal Physiol. 2012 Dec 15;303(12):F1629-40. doi: 10.1152/ajprenal.00246.2012. Epub 2012 Sep 26. Am J Physiol Renal Physiol. 2012. PMID: 23019230 Free PMC article.
315 results