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Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2.
Smith AH, Ovesen PL, Skeldal S, Yeo S, Jensen KP, Olsen D, Diazgranados N, Zhao H, Farrer LA, Goldman D, Glerup S, Kranzler HR, Nykjaer A, Gelernter J. Smith AH, et al. Among authors: skeldal s. Alcohol Clin Exp Res. 2018 Dec;42(12):2337-2348. doi: 10.1111/acer.13890. Epub 2018 Oct 25. Alcohol Clin Exp Res. 2018. PMID: 30252935 Free PMC article.
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis.
Skeldal S, Sykes AM, Glerup S, Matusica D, Palstra N, Autio H, Boskovic Z, Madsen P, Castrén E, Nykjaer A, Coulson EJ. Skeldal S, et al. J Biol Chem. 2012 Dec 21;287(52):43798-809. doi: 10.1074/jbc.M112.374710. Epub 2012 Oct 26. J Biol Chem. 2012. PMID: 23105113 Free PMC article.
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A. Glerup S, et al. Among authors: skeldal s. Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022. Neuron. 2014. PMID: 24908487 Free article.
Exploring the sortilin related receptor, SorLA, in depression.
Buttenschøn HN, Elfving B, Nielsen M, Skeldal S, Kaas M, Mors O, Glerup S. Buttenschøn HN, et al. Among authors: skeldal s. J Affect Disord. 2018 May;232:260-267. doi: 10.1016/j.jad.2018.02.050. Epub 2018 Feb 21. J Affect Disord. 2018. PMID: 29499509
Alternative splicing regulates adaptor protein binding, trafficking, and activity of the Vps10p domain receptor SorCS2 in neuronal development.
Skeldal S, Voss LF, Lende J, Pedersen SB, Mølgaard S, Kaas M, Demange P, Bentsen AH, Fuglsang M, Sander MR, Buttenschøn H, Gustafsen C, Madsen P, Glerup S. Skeldal S, et al. J Biol Chem. 2023 Sep;299(9):105102. doi: 10.1016/j.jbc.2023.105102. Epub 2023 Jul 26. J Biol Chem. 2023. PMID: 37507021 Free PMC article.
20 results