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6 results
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Significant increase in systemic exposure of atorvastatin after biliopancreatic diversion with duodenal switch.
Clin Pharmacol Ther. 2010 Jun;87(6):699-705. doi: 10.1038/clpt.2010.32. Epub 2010 May 5.
Clin Pharmacol Ther. 2010.
PMID: 20445535
Clinical Trial.
Significantly altered systemic exposure to atorvastatin acid following gastric bypass surgery in morbidly obese patients.
Skottheim IB, Stormark K, Christensen H, Jakobsen GS, Hjelmesaeth J, Jenssen T, Reubsaet JL, Sandbu R, Asberg A.
Skottheim IB, et al.
Clin Pharmacol Ther. 2009 Sep;86(3):311-8. doi: 10.1038/clpt.2009.82. Epub 2009 Jun 3.
Clin Pharmacol Ther. 2009.
PMID: 19494810
Clinical Trial.
Item in Clipboard
Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and intestine on interpatient pharmacokinetic variability of atorvastatin in obese subjects.
Ulvestad M, Skottheim IB, Jakobsen GS, Bremer S, Molden E, Asberg A, Hjelmesæth J, Andersson TB, Sandbu R, Christensen H.
Ulvestad M, et al. Among authors: skottheim ib.
Clin Pharmacol Ther. 2013 Mar;93(3):275-82. doi: 10.1038/clpt.2012.261. Epub 2012 Dec 27.
Clin Pharmacol Ther. 2013.
PMID: 23361102
Item in Clipboard
Long-term effects of gastric bypass and duodenal switch on systemic exposure of atorvastatin.
Jakobsen GS, Skottheim IB, Sandbu R, Christensen H, Røislien J, Asberg A, Hjelmesæth J.
Jakobsen GS, et al. Among authors: skottheim ib.
Surg Endosc. 2013 Jun;27(6):2094-101. doi: 10.1007/s00464-012-2716-3. Epub 2012 Dec 18.
Surg Endosc. 2013.
PMID: 23247745
Free PMC article.
Clinical Trial.
Item in Clipboard
Atorvastatin metabolite measurements as a diagnostic tool for statin-induced myopathy.
Skottheim IB, Bogsrud MP, Hermann M, Retterstøl K, Åsberg A.
Skottheim IB, et al.
Mol Diagn Ther. 2011 Aug 1;15(4):221-7. doi: 10.1007/BF03256413.
Mol Diagn Ther. 2011.
PMID: 21815705
Clinical Trial.
Item in Clipboard
Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro.
Skottheim IB, Gedde-Dahl A, Hejazifar S, Hoel K, Asberg A.
Skottheim IB, et al.
Eur J Pharm Sci. 2008 Apr 23;33(4-5):317-25. doi: 10.1016/j.ejps.2007.12.009. Epub 2008 Jan 18.
Eur J Pharm Sci. 2008.
PMID: 18294823
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