Southall N - Search Results

1

Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.

Hu X, Myhr C, Huang Z, Xiao J, Barnaeva E, Ho BA, Agoulnik IU, Ferrer M, Marugan JJ, Southall N, Agoulnik AI. Hu X, et al. Among authors: southall n. Biochemistry. 2016 Mar 29;55(12):1772-83. doi: 10.1021/acs.biochem.5b01195. Epub 2016 Mar 4. Biochemistry. 2016. PMID: 26866459 Free PMC article.

2

Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor.

Titus S, Neumann S, Zheng W, Southall N, Michael S, Klumpp C, Yasgar A, Shinn P, Thomas CJ, Inglese J, Gershengorn MC, Austin CP. Titus S, et al. Among authors: southall n. J Biomol Screen. 2008 Feb;13(2):120-7. doi: 10.1177/1087057107313786. Epub 2008 Jan 23. J Biomol Screen. 2008. PMID: 18216391 Free PMC article.

3

The pilot phase of the NIH Chemical Genomics Center.

Thomas CJ, Auld DS, Huang R, Huang W, Jadhav A, Johnson RL, Leister W, Maloney DJ, Marugan JJ, Michael S, Simeonov A, Southall N, Xia M, Zheng W, Inglese J, Austin CP. Thomas CJ, et al. Among authors: southall n. Curr Top Med Chem. 2009;9(13):1181-93. doi: 10.2174/156802609789753644. Curr Top Med Chem. 2009. PMID: 19807664 Free PMC article. Review.

4

Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators.

Marugan JJ, Zheng W, Motabar O, Southall N, Goldin E, Sidransky E, Aungst RA, Liu K, Sadhukhan SK, Austin CP. Marugan JJ, et al. Among authors: southall n. Eur J Med Chem. 2010 May;45(5):1880-97. doi: 10.1016/j.ejmech.2010.01.027. Epub 2010 Feb 1. Eur J Med Chem. 2010. PMID: 20206419 Free PMC article.

5

High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurements.

Chen CZ, Kulakova L, Southall N, Marugan JJ, Galkin A, Austin CP, Herzberg O, Zheng W. Chen CZ, et al. Among authors: southall n. Antimicrob Agents Chemother. 2011 Feb;55(2):667-75. doi: 10.1128/AAC.00618-10. Epub 2010 Nov 15. Antimicrob Agents Chemother. 2011. PMID: 21078930 Free PMC article.

6

Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor.

McCoy JG, Marugan JJ, Liu K, Zheng W, Southall N, Huang W, Heilig M, Austin CP. McCoy JG, et al. Among authors: southall n. ACS Chem Neurosci. 2010 Aug 18;1(8):559-574. doi: 10.1021/cn100040h. ACS Chem Neurosci. 2010. PMID: 21116448 Free PMC article.

7

Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity.

Marugan JJ, Zheng W, Motabar O, Southall N, Goldin E, Westbroek W, Stubblefield BK, Sidransky E, Aungst RA, Lea WA, Simeonov A, Leister W, Austin CP. Marugan JJ, et al. Among authors: southall n. J Med Chem. 2011 Feb 24;54(4):1033-58. doi: 10.1021/jm1008902. Epub 2011 Jan 20. J Med Chem. 2011. PMID: 21250698 Free PMC article.

8

High throughput screening for inhibitors of alpha-galactosidase.

Motabar O, Liu K, Southall N, Marugan JJ, Goldin E, Sidransky E, Zheng W. Motabar O, et al. Among authors: southall n. Curr Chem Genomics. 2010 Dec 3;4:67-73. doi: 10.2174/1875397301004010067. Curr Chem Genomics. 2010. PMID: 21331308 Free PMC article.

9

Discovery, synthesis, and biological evaluation of novel SMN protein modulators.

Xiao J, Marugan JJ, Zheng W, Titus S, Southall N, Cherry JJ, Evans M, Androphy EJ, Austin CP. Xiao J, et al. Among authors: southall n. J Med Chem. 2011 Sep 22;54(18):6215-33. doi: 10.1021/jm200497t. Epub 2011 Aug 19. J Med Chem. 2011. PMID: 21819082 Free PMC article.

10

A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide.

Motabar O, Goldin E, Leister W, Liu K, Southall N, Huang W, Marugan JJ, Sidransky E, Zheng W. Motabar O, et al. Among authors: southall n. Anal Bioanal Chem. 2012 Jan;402(2):731-9. doi: 10.1007/s00216-011-5496-z. Epub 2011 Oct 28. Anal Bioanal Chem. 2012. PMID: 22033823 Free PMC article.

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