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Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Kristiansson K, Perola M, Tikkanen E, Kettunen J, Surakka I, Havulinna AS, Stancáková A, Barnes C, Widen E, Kajantie E, Eriksson JG, Viikari J, Kähönen M, Lehtimäki T, Raitakari OT, Hartikainen AL, Ruokonen A, Pouta A, Jula A, Kangas AJ, Soininen P, Ala-Korpela M, Männistö S, Jousilahti P, Bonnycastle LL, Järvelin MR, Kuusisto J, Collins FS, Laakso M, Hurles ME, Palotie A, Peltonen L, Ripatti S, Salomaa V. Kristiansson K, et al. Among authors: stancakova a. Circ Cardiovasc Genet. 2012 Apr 1;5(2):242-9. doi: 10.1161/CIRCGENETICS.111.961482. Epub 2012 Mar 7. Circ Cardiovasc Genet. 2012. PMID: 22399527 Free PMC article.
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance.
Stancáková A, Pihlajamäki J, Kuusisto J, Stefan N, Fritsche A, Häring H, Andreozzi F, Succurro E, Sesti G, Boesgaard TW, Hansen T, Pedersen O, Jansson PA, Hammarstedt A, Smith U, Laakso M; EUGENE2 Consortium. Stancáková A, et al. J Clin Endocrinol Metab. 2008 May;93(5):1924-30. doi: 10.1210/jc.2007-2218. Epub 2008 Feb 19. J Clin Endocrinol Metab. 2008. PMID: 18285412
Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.
Friedrich B, Weyrich P, Stancáková A, Wang J, Kuusisto J, Laakso M, Sesti G, Succurro E, Smith U, Hansen T, Pedersen O, Machicao F, Schäfer S, Lang F, Risler T, Ullrich S, Stefan N, Fritsche A, Häring HU. Friedrich B, et al. Among authors: stancakova a. PLoS One. 2008;3(11):e3506. doi: 10.1371/journal.pone.0003506. Epub 2008 Nov 5. PLoS One. 2008. PMID: 18985156 Free PMC article.
Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.
Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU. Müssig K, et al. Among authors: stancakova a. J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. doi: 10.1210/jc.2008-1048. Epub 2009 Jan 13. J Clin Endocrinol Metab. 2009. PMID: 19141580
Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.
Weyrich P, Staiger H, Stancáková A, Schäfer SA, Kirchhoff K, Ullrich S, Ranta F, Gallwitz B, Stefan N, Machicao F, Kuusisto J, Laakso M, Fritsche A, Häring HU. Weyrich P, et al. Among authors: stancakova a. BMC Med Genet. 2009 Aug 14;10:77. doi: 10.1186/1471-2350-10-77. BMC Med Genet. 2009. PMID: 19682370 Free PMC article.
Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism--the Finnish Diabetes Prevention Study.
Lappalainen T, Kolehmainen M, Schwab US, Tolppanen AM, Stančáková A, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Aunola S, Ilanne-Parikka P, Herder C, Koenig W, Gylling H, Kolb H, Tuomilehto J, Kuusisto J, Uusitupa M; Finnish Diabetes Prevention Study Group. Lappalainen T, et al. Among authors: stancakova a. Nutr Metab Cardiovasc Dis. 2011 Sep;21(9):691-8. doi: 10.1016/j.numecd.2010.01.006. Epub 2010 Apr 18. Nutr Metab Cardiovasc Dis. 2011. PMID: 20400278
152 results