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Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase.
Kast R, Schirok H, Figueroa-Pérez S, Mittendorf J, Gnoth MJ, Apeler H, Lenz J, Franz JK, Knorr A, Hütter J, Lobell M, Zimmermann K, Münter K, Augstein KH, Ehmke H, Stasch JP. Kast R, et al. Among authors: stasch jp. Br J Pharmacol. 2007 Dec;152(7):1070-80. doi: 10.1038/sj.bjp.0707484. Epub 2007 Oct 15. Br J Pharmacol. 2007. PMID: 17934515 Free PMC article.
Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.
Pankey EA, Bhartiya M, Badejo AM Jr, Haider U, Stasch JP, Murthy SN, Nossaman BD, Kadowitz PJ. Pankey EA, et al. Among authors: stasch jp. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H792-802. doi: 10.1152/ajpheart.00953.2010. Epub 2011 Jan 7. Am J Physiol Heart Circ Physiol. 2011. PMID: 21217076 Free PMC article.
Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors.
Schirok H, Kast R, Figueroa-Pérez S, Bennabi S, Gnoth MJ, Feurer A, Heckroth H, Thutewohl M, Paulsen H, Knorr A, Hütter J, Lobell M, Münter K, Geiss V, Ehmke H, Lang D, Radtke M, Mittendorf J, Stasch JP. Schirok H, et al. Among authors: stasch jp. ChemMedChem. 2008 Dec;3(12):1893-904. doi: 10.1002/cmdc.200800211. ChemMedChem. 2008. PMID: 18973168
200 results