Stearns RA - Search Results

1

Characterization of two cyclic metabolites of sitagliptin.

Liu DQ, Arison BH, Stearns RA, Kim D, Vincent SH. Liu DQ, et al. Among authors: stearns ra. Drug Metab Dispos. 2007 Apr;35(4):521-4. doi: 10.1124/dmd.106.013128. Epub 2007 Jan 12. Drug Metab Dispos. 2007. PMID: 17220240

2

Disposition of the dipeptidyl peptidase 4 inhibitor sitagliptin in rats and dogs.

Beconi MG, Reed JR, Teffera Y, Xia YQ, Kochansky CJ, Liu DQ, Xu S, Elmore CS, Ciccotto S, Hora DF, Stearns RA, Vincent SH. Beconi MG, et al. Among authors: stearns ra. Drug Metab Dispos. 2007 Apr;35(4):525-32. doi: 10.1124/dmd.106.013110. Epub 2007 Jan 12. Drug Metab Dispos. 2007. PMID: 17220241

3

Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine.

Balani SK, Arison BH, Mathai L, Kauffman LR, Miller RR, Stearns RA, Chen IW, Lin JH. Balani SK, et al. Among authors: stearns ra. Drug Metab Dispos. 1995 Feb;23(2):266-70. Drug Metab Dispos. 1995. PMID: 7736923 Clinical Trial.

4

Orally active inhibitors of human leukocyte elastase. III. Identification and characterization of metabolites of L-694,458 by liquid chromatography-tandem mass spectrometry.

Luffer-Atlas D, Vincent SH, Painter SK, Arison BH, Stearns RA, Chiu SH. Luffer-Atlas D, et al. Among authors: stearns ra. Drug Metab Dispos. 1997 Aug;25(8):940-52. Drug Metab Dispos. 1997. PMID: 9280402

5

Evidence for a 1,2-hydride shift in the microsomal metabolism of the heterocycle L-158,338, a nonpeptide angiotensin II receptor antagonist.

Stearns RA, Miller RR, Arison BH, Rosegay A, Smith JL, Mantlo NB, Chiu SH. Stearns RA, et al. Drug Metab Dispos. 1993 Jul-Aug;21(4):670-6. Drug Metab Dispos. 1993. PMID: 8104127

6

Disposition of L-732,531, a potent immunosuppressant, in rats and baboons.

Karanam BV, Miller RR, Colletti A, Montgomery T, Carey KD, Hawkins T, Tang YS, Lavin M, Stearns RA, Chiu SH, Vincent SH. Karanam BV, et al. Among authors: stearns ra. Drug Metab Dispos. 1998 Oct;26(10):949-57. Drug Metab Dispos. 1998. PMID: 9763399

7

Biotransformation of finasteride (MK-0906) by Selenastrum capricornutum (green algae).

Venkataramani ES, Carlin JR, Dolling U, Christofalo P, Magliette RJ, Arison BH, Stearns RA. Venkataramani ES, et al. Among authors: stearns ra. Ann N Y Acad Sci. 1994 Nov 30;745:51-60. doi: 10.1111/j.1749-6632.1994.tb44363.x. Ann N Y Acad Sci. 1994. PMID: 7832532

8

A novel P450-catalyzed transformation of the 2,2,6,6-tetramethyl piperidine moiety to a 2,2-dimethyl pyrrolidine in human liver microsomes: characterization by high resolution quadrupole-time-of-flight mass spectrometry and 1H-NMR.

Yin W, Doss GA, Stearns RA, Chaudhary AG, Hop CE, Franklin RB, Kumar S. Yin W, et al. Among authors: stearns ra. Drug Metab Dispos. 2003 Feb;31(2):215-23. doi: 10.1124/dmd.31.2.215. Drug Metab Dispos. 2003. PMID: 12527703

9

Metabolic activation of fluoropyrrolidine dipeptidyl peptidase-IV inhibitors by rat liver microsomes.

Xu S, Zhu B, Teffera Y, Pan DE, Caldwell CG, Doss G, Stearns RA, Evans DC, Beconi MG. Xu S, et al. Among authors: stearns ra. Drug Metab Dispos. 2005 Jan;33(1):121-30. doi: 10.1124/dmd.104.001842. Epub 2004 Oct 14. Drug Metab Dispos. 2005. PMID: 15486074

10

Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists.

Kopka IE, Lin LS, Mumford RA, Lanza T Jr, Magriotis PA, Young D, DeLaszlo SE, MacCoss M, Mills SG, Van Riper G, McCauley E, Lyons K, Vincent S, Egger LA, Kidambi U, Stearns R, Colletti A, Teffera Y, Tong S, Owens K, Levorse D, Schmidt JA, Hagmann WK. Kopka IE, et al. Among authors: stearns r. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2415-8. doi: 10.1016/s0960-894x(02)00460-2. Bioorg Med Chem Lett. 2002. PMID: 12161146

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