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Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5.
Hatzikotoulas K, Roposch A; DDH Case Control Consortium; Shah KM, Clark MJ, Bratherton S, Limbani V, Steinberg J, Zengini E, Warsame K, Ratnayake M, Tselepi M, Schwartzentruber J, Loughlin J, Eastwood DM, Zeggini E, Wilkinson JM. Hatzikotoulas K, et al. Among authors: steinberg j. Commun Biol. 2018 May 31;1:56. doi: 10.1038/s42003-018-0052-4. eCollection 2018. Commun Biol. 2018. PMID: 30273415 Free PMC article.
A novel variant in GLIS3 is associated with osteoarthritis.
Casalone E, Tachmazidou I, Zengini E, Hatzikotoulas K, Hackinger S, Suveges D, Steinberg J, Rayner NW; arcOGEN Consortium; Wilkinson JM, Panoutsopoulou K, Zeggini E. Casalone E, et al. Among authors: steinberg j. Ann Rheum Dis. 2018 Apr;77(4):620-623. doi: 10.1136/annrheumdis-2017-211848. Epub 2018 Feb 7. Ann Rheum Dis. 2018. PMID: 29436472 Free PMC article.
A molecular quantitative trait locus map for osteoarthritis.
Steinberg J, Southam L, Roumeliotis TI, Clark MJ, Jayasuriya RL, Swift D, Shah KM, Butterfield NC, Brooks RA, McCaskie AW, Bassett JHD, Williams GR, Choudhary JS, Wilkinson JM, Zeggini E. Steinberg J, et al. Nat Commun. 2021 Feb 26;12(1):1309. doi: 10.1038/s41467-021-21593-7. Nat Commun. 2021. PMID: 33637762 Free PMC article.
Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.
Steinberg J, Ritchie GRS, Roumeliotis TI, Jayasuriya RL, Clark MJ, Brooks RA, Binch ALA, Shah KM, Coyle R, Pardo M, Le Maitre CL, Ramos YFM, Nelissen RGHH, Meulenbelt I, McCaskie AW, Choudhary JS, Wilkinson JM, Zeggini E. Steinberg J, et al. Sci Rep. 2017 Aug 21;7(1):8935. doi: 10.1038/s41598-017-09335-6. Sci Rep. 2017. PMID: 28827734 Free PMC article.
Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus.
Hackinger S, Trajanoska K, Styrkarsdottir U, Zengini E, Steinberg J, Ritchie GRS, Hatzikotoulas K, Gilly A, Evangelou E, Kemp JP; arcOGEN Consortium, GEFOS Consortium; Evans D, Ingvarsson T, Jonsson H, Thorsteinsdottir U, Stefansson K, McCaskie AW, Brooks RA, Wilkinson JM, Rivadeneira F, Zeggini E. Hackinger S, et al. Among authors: steinberg j. Hum Mol Genet. 2017 Oct 1;26(19):3850-3858. doi: 10.1093/hmg/ddx285. Hum Mol Genet. 2017. PMID: 28934396 Free PMC article.
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Zengini E, et al. Among authors: steinberg j. Nat Genet. 2018 Apr;50(4):549-558. doi: 10.1038/s41588-018-0079-y. Epub 2018 Mar 20. Nat Genet. 2018. PMID: 29559693 Free PMC article.
1,559 results