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Structural basis of RasGRP binding to high-affinity PKC ligands.
Rong SB, Enyedy IJ, Qiao L, Zhao L, Ma D, Pearce LL, Lorenzo PS, Stone JC, Blumberg PM, Wang S, Kozikowski AP. Rong SB, et al. Among authors: stone jc. J Med Chem. 2002 Feb 14;45(4):853-60. doi: 10.1021/jm010422z. J Med Chem. 2002. PMID: 11831896
A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha.
Pu Y, Perry NA, Yang D, Lewin NE, Kedei N, Braun DC, Choi SH, Blumberg PM, Garfield SH, Stone JC, Duan D, Marquez VE. Pu Y, et al. Among authors: stone jc. J Biol Chem. 2005 Jul 22;280(29):27329-38. doi: 10.1074/jbc.M414132200. Epub 2005 May 27. J Biol Chem. 2005. PMID: 15923197 Free article.
RasGRP links T-cell receptor signaling to Ras.
Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC. Ebinu JO, et al. Among authors: stone jc. Blood. 2000 May 15;95(10):3199-203. Blood. 2000. PMID: 10807788 Free article.
183 results