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Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes.
Cázares A, Galman JL, Crago LG, Smith ME, Strafford J, Ríos-Solís L, Lye GJ, Dalby PA, Hailes HC. Cázares A, et al. Among authors: strafford j. Org Biomol Chem. 2010 Mar 21;8(6):1301-9. doi: 10.1039/b924144b. Epub 2010 Feb 5. Org Biomol Chem. 2010. PMID: 20204200
Directed evolution to re-adapt a co-evolved network within an enzyme.
Strafford J, Payongsri P, Hibbert EG, Morris P, Batth SS, Steadman D, Smith ME, Ward JM, Hailes HC, Dalby PA. Strafford J, et al. J Biotechnol. 2012 Jan;157(1):237-45. doi: 10.1016/j.jbiotec.2011.11.017. Epub 2011 Nov 29. J Biotechnol. 2012. PMID: 22154561 Free PMC article.