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Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor.
Uchinoumi H, Yano M, Suetomi T, Ono M, Xu X, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M. Uchinoumi H, et al. Among authors: suetomi t. Circ Res. 2010 Apr 30;106(8):1413-24. doi: 10.1161/CIRCRESAHA.109.209312. Epub 2010 Mar 11. Circ Res. 2010. PMID: 20224043 Free PMC article.
Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²⁺release leading to catecholaminergic polymorphic ventricular tachycardia.
Suetomi T, Yano M, Uchinoumi H, Fukuda M, Hino A, Ono M, Xu X, Tateishi H, Okuda S, Doi M, Kobayashi S, Ikeda Y, Yamamoto T, Ikemoto N, Matsuzaki M. Suetomi T, et al. Circulation. 2011 Aug 9;124(6):682-94. doi: 10.1161/CIRCULATIONAHA.111.023259. Epub 2011 Jul 18. Circulation. 2011. PMID: 21768539 Free PMC article.
Factors Influencing Acceptance of the Chairperson Position at Annual Scientific Meetings of the Japanese Circulation Society　- A Questionnaire Survey in Chugoku District.
Fukue N, Ishida M, Taniyama M, Mukai-Yatagai N, Sakamoto T, Tamada T, Suetomi T, Tanabe K, Nakano Y. Fukue N, et al. Among authors: suetomi t. Circ Rep. 2023 May 12;5(6):260-264. doi: 10.1253/circrep.CR-23-0011. eCollection 2023 Jun 9. Circ Rep. 2023. PMID: 37305796 Free PMC article.
Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts.
Tateishi H, Yano M, Mochizuki M, Suetomi T, Ono M, Xu X, Uchinoumi H, Okuda S, Oda T, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M. Tateishi H, et al. Among authors: suetomi t. Cardiovasc Res. 2009 Feb 15;81(3):536-45. doi: 10.1093/cvr/cvn303. Epub 2008 Nov 7. Cardiovasc Res. 2009. PMID: 18996969 Free PMC article.
Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor.
Kobayashi S, Yano M, Suetomi T, Ono M, Tateishi H, Mochizuki M, Xu X, Uchinoumi H, Okuda S, Yamamoto T, Koseki N, Kyushiki H, Ikemoto N, Matsuzaki M. Kobayashi S, et al. Among authors: suetomi t. J Am Coll Cardiol. 2009 May 26;53(21):1993-2005. doi: 10.1016/j.jacc.2009.01.065. J Am Coll Cardiol. 2009. PMID: 19460614 Free PMC article.
59 results