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Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia.
Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ, Neurauter CG, Suganthan R, Atneosen-Åsegg M, Fleming AM, Saugstad OD, Burrows CJ, Luna L, Bjørås M. Sejersted Y, et al. Among authors: suganthan r. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18802-7. doi: 10.1073/pnas.1106880108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065741 Free PMC article.
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress.
Rolseth V, Krokeide SZ, Kunke D, Neurauter CG, Suganthan R, Sejersted Y, Hildrestrand GA, Bjørås M, Luna L. Rolseth V, et al. Among authors: suganthan r. Biochim Biophys Acta. 2013 May;1833(5):1157-64. doi: 10.1016/j.bbamcr.2012.12.024. Epub 2013 Jan 7. Biochim Biophys Acta. 2013. PMID: 23305905 Free article.
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P. Skarpengland T, et al. Among authors: suganthan r. Sci Rep. 2016 Jun 22;6:28337. doi: 10.1038/srep28337. Sci Rep. 2016. PMID: 27328939 Free PMC article.
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.
Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M. Rolseth V, et al. Among authors: suganthan r. Sci Rep. 2017 Jun 29;7(1):4384. doi: 10.1038/s41598-017-04472-4. Sci Rep. 2017. PMID: 28663564 Free PMC article.
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Hildrestrand GA, Rolseth V, Kunath N, Suganthan R, Jensen V, Bugaj AM, Fernandez-Berrocal MS, Sikko SB, Vetlesen S, Kuśnierczyk A, Olsen AK, Gützkow KB, Rowe AD, Wang W, Moldestad O, Syrstad MD, Slupphaug G, Eide L, Klungland A, Sætrom P, Luna L, Ye J, Scheffler K, Bjørås M. Hildrestrand GA, et al. Among authors: suganthan r. Commun Biol. 2021 Dec 2;4(1):1354. doi: 10.1038/s42003-021-02864-x. Commun Biol. 2021. PMID: 34857879 Free PMC article.
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Bjørge MD, Hildrestrand GA, Scheffler K, Suganthan R, Rolseth V, Kuśnierczyk A, Rowe AD, Vågbø CB, Vetlesen S, Eide L, Slupphaug G, Nakabeppu Y, Bredy TW, Klungland A, Bjørås M. Bjørge MD, et al. Among authors: suganthan r. Cell Rep. 2015 Dec 29;13(12):2671-8. doi: 10.1016/j.celrep.2015.12.001. Epub 2015 Dec 17. Cell Rep. 2015. PMID: 26711335 Free article.
31 results