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Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.
Feng L, Maddox MM, Alam MZ, Tsutsumi LS, Narula G, Bruhn DF, Wu X, Sandhaus S, Lee RB, Simmons CJ, Tse-Dinh YC, Hurdle JG, Lee RE, Sun D. Feng L, et al. Among authors: sun d. J Med Chem. 2014 Oct 23;57(20):8398-420. doi: 10.1021/jm500853v. Epub 2014 Oct 7. J Med Chem. 2014. PMID: 25238443 Free PMC article.
Discovery of novel isoxazolines as anti-tuberculosis agents.
Tangallapally RP, Sun D, Rakesh, Budha N, Lee RE, Lenaerts AJ, Meibohm B, Lee RE. Tangallapally RP, et al. Among authors: sun d. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6638-42. doi: 10.1016/j.bmcl.2007.09.048. Epub 2007 Sep 15. Bioorg Med Chem Lett. 2007. PMID: 17937983 Free PMC article.
Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC).
Sivendran S, Jones V, Sun D, Wang Y, Grzegorzewicz AE, Scherman MS, Napper AD, McCammon JA, Lee RE, Diamond SL, McNeil M. Sivendran S, et al. Among authors: sun d. Bioorg Med Chem. 2010 Jan 15;18(2):896-908. doi: 10.1016/j.bmc.2009.11.033. Epub 2009 Nov 20. Bioorg Med Chem. 2010. PMID: 19969466 Free PMC article.
The structure-activity relationship of urea derivatives as anti-tuberculosis agents.
Brown JR, North EJ, Hurdle JG, Morisseau C, Scarborough JS, Sun D, Korduláková J, Scherman MS, Jones V, Grzegorzewicz A, Crew RM, Jackson M, McNeil MR, Lee RE. Brown JR, et al. Among authors: sun d. Bioorg Med Chem. 2011 Sep 15;19(18):5585-95. doi: 10.1016/j.bmc.2011.07.034. Epub 2011 Jul 24. Bioorg Med Chem. 2011. PMID: 21840723 Free PMC article.
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