Sundheim O - Search Results

1

A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.

Hu Y, Ericsson I, Torseth K, Methot SP, Sundheim O, Liabakk NB, Slupphaug G, Di Noia JM, Krokan HE, Kavli B. Hu Y, et al. Among authors: sundheim o. J Mol Biol. 2013 Jan 23;425(2):424-43. doi: 10.1016/j.jmb.2012.11.026. Epub 2012 Nov 23. J Mol Biol. 2013. PMID: 23183374

2

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup.

Kavli B, Sundheim O, Akbari M, Otterlei M, Nilsen H, Skorpen F, Aas PA, Hagen L, Krokan HE, Slupphaug G. Kavli B, et al. Among authors: sundheim o. J Biol Chem. 2002 Oct 18;277(42):39926-36. doi: 10.1074/jbc.M207107200. Epub 2002 Aug 2. J Biol Chem. 2002. PMID: 12161446 Free article.

3

Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms.

Pettersen HS, Sundheim O, Gilljam KM, Slupphaug G, Krokan HE, Kavli B. Pettersen HS, et al. Among authors: sundheim o. Nucleic Acids Res. 2007;35(12):3879-92. doi: 10.1093/nar/gkm372. Epub 2007 May 30. Nucleic Acids Res. 2007. PMID: 17537817 Free PMC article.

4

Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.

Hagen L, Kavli B, Sousa MM, Torseth K, Liabakk NB, Sundheim O, Pena-Diaz J, Otterlei M, Hørning O, Jensen ON, Krokan HE, Slupphaug G. Hagen L, et al. Among authors: sundheim o. EMBO J. 2008 Jan 9;27(1):51-61. doi: 10.1038/sj.emboj.7601958. Epub 2007 Dec 13. EMBO J. 2008. PMID: 18079698 Free PMC article.

5

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage.

Hanssen-Bauer A, Solvang-Garten K, Sundheim O, Peña-Diaz J, Andersen S, Slupphaug G, Krokan HE, Wilson DM 3rd, Akbari M, Otterlei M. Hanssen-Bauer A, et al. Among authors: sundheim o. Environ Mol Mutagen. 2011 Oct;52(8):623-35. doi: 10.1002/em.20663. Epub 2011 Jul 22. Environ Mol Mutagen. 2011. PMID: 21786338 Free PMC article.

6

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.

Aas PA, Otterlei M, Falnes PO, Vågbø CB, Skorpen F, Akbari M, Sundheim O, Bjørås M, Slupphaug G, Seeberg E, Krokan HE. Aas PA, et al. Among authors: sundheim o. Nature. 2003 Feb 20;421(6925):859-63. doi: 10.1038/nature01363. Nature. 2003. PMID: 12594517

7

Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.

Westbye MP, Feyzi E, Aas PA, Vågbø CB, Talstad VA, Kavli B, Hagen L, Sundheim O, Akbari M, Liabakk NB, Slupphaug G, Otterlei M, Krokan HE. Westbye MP, et al. Among authors: sundheim o. J Biol Chem. 2008 Sep 5;283(36):25046-56. doi: 10.1074/jbc.M803776200. Epub 2008 Jul 3. J Biol Chem. 2008. PMID: 18603530 Free PMC article.

8

AlkB demethylases flip out in different ways.

Sundheim O, Talstad VA, Vågbø CB, Slupphaug G, Krokan HE. Sundheim O, et al. DNA Repair (Amst). 2008 Nov 1;7(11):1916-23. doi: 10.1016/j.dnarep.2008.07.015. Epub 2008 Sep 6. DNA Repair (Amst). 2008. PMID: 18723127 Review.

9

RNA base damage and repair.

Feyzi E, Sundheim O, Westbye MP, Aas PA, Vågbø CB, Otterlei M, Slupphaug G, Krokan HE. Feyzi E, et al. Among authors: sundheim o. Curr Pharm Biotechnol. 2007 Dec;8(6):326-31. doi: 10.2174/138920107783018363. Curr Pharm Biotechnol. 2007. PMID: 18289040 Review.

10

Trypanosoma cruzi contains a single detectable uracil-DNA glycosylase and repairs uracil exclusively via short patch base excision repair.

Peña-Diaz J, Akbari M, Sundheim O, Farez-Vidal ME, Andersen S, Sneve R, Gonzalez-Pacanowska D, Krokan HE, Slupphaug G. Peña-Diaz J, et al. Among authors: sundheim o. J Mol Biol. 2004 Sep 17;342(3):787-99. doi: 10.1016/j.jmb.2004.07.043. J Mol Biol. 2004. PMID: 15342237

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