Sylte I - Search Results

1

Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models.

Høgmoen Åstrand OA, Gikling I, Sylte I, Rustan AC, Thoresen GH, Rongved P, Kase ET. Høgmoen Åstrand OA, et al. Among authors: sylte i. Eur J Med Chem. 2014 Mar 3;74:258-63. doi: 10.1016/j.ejmech.2014.01.003. Epub 2014 Jan 11. Eur J Med Chem. 2014. PMID: 24480357

2

Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor.

Hjerde E, Dahl SG, Sylte I. Hjerde E, et al. Among authors: sylte i. Eur J Med Chem. 2005 Feb;40(2):185-94. doi: 10.1016/j.ejmech.2004.10.010. Eur J Med Chem. 2005. PMID: 15694653

3

Discovery of potent thermolysin inhibitors using structure based virtual screening and binding assays.

Khan MT, Fuskevåg OM, Sylte I. Khan MT, et al. Among authors: sylte i. J Med Chem. 2009 Jan 8;52(1):48-61. doi: 10.1021/jm8008019. J Med Chem. 2009. PMID: 19072688

4

Synthesis, molecular modeling studies and biological evaluation of fluorine substituted analogs of GW 501516.

Ciocoiu CC, Ravna AW, Sylte I, Rustan AC, Hansen TV. Ciocoiu CC, et al. Among authors: sylte i. Bioorg Med Chem. 2011 Dec 1;19(23):6982-8. doi: 10.1016/j.bmc.2011.10.020. Epub 2011 Oct 17. Bioorg Med Chem. 2011. PMID: 22051054

5

The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism.

Hessvik NP, Bakke SS, Smith R, Ravna AW, Sylte I, Rustan AC, Thoresen GH, Kase ET. Hessvik NP, et al. Among authors: sylte i. J Steroid Biochem Mol Biol. 2012 Feb;128(3-5):154-64. doi: 10.1016/j.jsbmb.2011.10.006. Epub 2011 Oct 25. J Steroid Biochem Mol Biol. 2012. PMID: 22051079

6

Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol.

Gabrielsen M, Kurczab R, Ravna AW, Kufareva I, Abagyan R, Chilmonczyk Z, Bojarski AJ, Sylte I. Gabrielsen M, et al. Among authors: sylte i. Eur J Med Chem. 2012 Jan;47(1):24-37. doi: 10.1016/j.ejmech.2011.09.056. Epub 2011 Oct 20. Eur J Med Chem. 2012. PMID: 22071255 Free PMC article.

7

Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol.

Strand OA, Sandberg M, Sylte I, Görbitz CH, Thoresen GH, Kase ET, Rongved P. Strand OA, et al. Among authors: sylte i. Bioorg Med Chem. 2014 Jan 1;22(1):643-50. doi: 10.1016/j.bmc.2013.10.024. Epub 2013 Nov 5. Bioorg Med Chem. 2014. PMID: 24268541

8

Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618.

Kaupang Å, Paulsen SM, Steindal CC, Ravna AW, Sylte I, Halvorsen TG, Thoresen GH, Hansen TV. Kaupang Å, et al. Among authors: sylte i. Eur J Med Chem. 2015 Apr 13;94:229-36. doi: 10.1016/j.ejmech.2015.03.006. Epub 2015 Mar 5. Eur J Med Chem. 2015. PMID: 25768705

9

Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors.

Åstrand OAH, Viktorsson EÖ, Kristensen AL, Ekeberg D, Røberg-Larsen H, Wilson SR, Gabrielsen M, Sylte I, Rustan AC, Thoresen GH, Rongved P, Kase ET. Åstrand OAH, et al. Among authors: sylte i. J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):323-330. doi: 10.1016/j.jsbmb.2016.07.010. Epub 2016 Jul 26. J Steroid Biochem Mol Biol. 2017. PMID: 27471149

10

Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations.

Viktorsson EÖ, Gabrielsen M, Kumarachandran N, Sylte I, Rongved P, Åstrand OA, Kase ET. Viktorsson EÖ, et al. Among authors: sylte i. Steroids. 2017 Feb;118:119-127. doi: 10.1016/j.steroids.2016.12.003. Epub 2016 Dec 21. Steroids. 2017. PMID: 28011133

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